Publications

Publications Search

Search for publications by author
Search for publications by abstract keyword(s)

MicroRNAs in common diseases and potential therapeutic applications

Abstract

1. Evidence gathered in the last few years has revealed microRNAs (miRNAs) fine-tune gene expression and play an instrumental role in various cellular processes including cell growth, differentiation, proliferation and apoptosis. 2. This review summarizes current knowledge of miRNA-pathways in the pathogenesis of cancer, cardiac diseases, neurodegenerative diseases, diabetes, autoimmune/inflammatory diseases and infection. 3. There is a great promise to target miRNAs as a novel approach to treat human diseases. 4. MiRNA-based therapies are being examined in both animal model studies and human clinical trials.

Type Journal
ISBN 0305-1870 (Linking)
Authors Tsai, L. M.; Yu, D.;
Responsible Garvan Author
Publisher Name CLIN EXP PHARMACOL P
Published Date 2010-01-01 00:00:00
Published Volume 37
Published Issue 1
Published Pages 102-107
Status Published in-print
URL link to publisher's version http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19671070
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/10573