Docking proteins comprise a distinct category of intracellular, noncatalytic signalling protein, that function downstream of a variety of receptor and receptor-associated tyrosine kinases and regulate diverse physiological and pathological processes. The growth factor receptor bound 2-associated binder/Daughter of Sevenless, insulin receptor substrate, fibroblast growth factor receptor substrate 2 and downstream of tyrosine kinases protein families fall into this category. This minireview focuses on the structure, function and regulation of these proteins.
|Authors||Brummer, T.; Schmitz-Peiffer, C.; Daly, R.J.|
|Responsible Garvan Author|
|Publisher Name||FEBS Journal|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20883498|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/10595|