Editorial overview: Lymphocyte activation and effector functions
Lymphocyte activation requires the integration of signals provided by the extracellular environment in the form of cell-like interactions and soluble factors, mainly cytokines. Engagement of specific receptors by these ligands trigger myriad signaling pathways that induce expression and/or activation of transcription factors that ultimately function to modulate gene expression, thereby imprinting the cell with a particular effector cell fate.
|Authors||Reynaud, C. A.; Tangye, S.|
|Responsible Garvan Author||Prof Stuart Tangye|
|Publisher Name||CURRENT OPINION IN IMMUNOLOGY|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/pubmed/24751355|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/12192|