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Prolonged venovenous extracorporeal membrane oxygenation without anticoagulation: a case of Goodpasture syndrome-related pulmonary haemorrhage


We present a 16-year-old male with severe acute respiratory and renal failure as a result of Goodpasture syndrome, requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) for pulmonary haemorrhage. The patient received no systemic anticoagulation for 25 of 26 ECMO days (20 days consecutively) and suffered no coagulation-related adverse events. The patient had a subtherapeutic anticoagulation profile according to recommended ECMO guidelines during most of this time. The patient made a full recovery without respiratory compromise, ECMO circuit failure, thrombotic events or the need for ongoing haemodialysis.

Type Journal
ISBN 1441-2772 (Print) 1441-2772 (Linking)
Authors Herbert, D. G.; Buscher, H.; Nair, P.;
Publisher Name Critical Care and Resuscitation
Published Date 2014-01-01
Published Volume 16
Published Issue 1
Published Pages 69-72
Status Published in-print
URL link to publisher's version
OpenAccess link to author's accepted manuscript version