Prolonged venovenous extracorporeal membrane oxygenation without anticoagulation: a case of Goodpasture syndrome-related pulmonary haemorrhage
We present a 16-year-old male with severe acute respiratory and renal failure as a result of Goodpasture syndrome, requiring venovenous extracorporeal membrane oxygenation (VV-ECMO) for pulmonary haemorrhage. The patient received no systemic anticoagulation for 25 of 26 ECMO days (20 days consecutively) and suffered no coagulation-related adverse events. The patient had a subtherapeutic anticoagulation profile according to recommended ECMO guidelines during most of this time. The patient made a full recovery without respiratory compromise, ECMO circuit failure, thrombotic events or the need for ongoing haemodialysis.
|ISBN||1441-2772 (Print) 1441-2772 (Linking)|
|Authors||Herbert, D. G. ; Buscher, H. ; Nair, P.;|
|Publisher Name||Critical Care and Resuscitation|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/pubmed/24588439|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/12755|