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The sum of all browning in FGF21 therapeutics

Abstract

FGF21 mimetics are a promising therapeutic tool, believed to exert their anti-obesity effect partly through browning of white fat. Veniant et al. (2015) and Samms et al. (2015) present evidence arguing against fat browning as the primary mechanism causal to weight loss following FGF21-based treatment in mice.

Type Journal
Authors Lee, P.; Swarbrick, M. M.; Greenfield, J. R.
Publisher Name Cell Metabolism
Published Date 2015-06-02 00:00:00
Published Volume 21
Published Issue 6
Published Pages 795-6
Status Published in-print
DOI 10.1016/j.cmet.2015.05.018
URL link to publisher's version http://www.ncbi.nlm.nih.gov/pubmed/26039444
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/12773