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Discovery and annotation of long noncoding RNAs

Abstract

Recent advances in RNA-sequencing technologies have led to the discovery of thousands of previously unannotated noncoding transcripts, including many long noncoding RNAs (lncRNAs) whose functions remain largely unknown. Here we discuss considerations and best practices in lncRNA identification and annotation, which we hope will foster functional and mechanistic exploration.

Type Journal
ISBN 1545-9985 (Electronic) 1545-9985 (Linking)
Authors Mattick, J. S.; Rinn, J. L.;
Responsible Garvan Author Prof John Mattick
Publisher Name NAT STRUCT MOL BIOL
Published Date 2015-01-01
Published Volume 22
Published Issue 1
Published Pages 5-7
Status Published in-print
URL link to publisher's version http://www.ncbi.nlm.nih.gov/pubmed/25565026
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/12838