Discovery and annotation of long noncoding RNAs
Recent advances in RNA-sequencing technologies have led to the discovery of thousands of previously unannotated noncoding transcripts, including many long noncoding RNAs (lncRNAs) whose functions remain largely unknown. Here we discuss considerations and best practices in lncRNA identification and annotation, which we hope will foster functional and mechanistic exploration.
|ISBN||1545-9985 (Electronic) 1545-9985 (Linking)|
|Authors||Mattick, J. S. ; Rinn, J. L.;|
|Responsible Garvan Author|
|Publisher Name||NAT STRUCT MOL BIOL|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/pubmed/25565026|