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Etiologic, environmental and inherited risk factors in sarcomas

Abstract

Sarcomas are a rare group of mesenchymal tumors affecting a younger population. The etiology remains unknown in most cases. Environmental factors that increase sarcoma risk include radiation exposure and chemical carcinogens. Several familial cancer syndromes confer sarcoma predisposition, such as the Li-Fraumeni Syndrome (LFS). In this increasingly genomic focussed era of medicine, it will be clinically important to understand the genetic basis of sarcoma risk. J. Surg. Oncol. 2015 111:490-495. (c) 2014 Wiley Periodicals, Inc.

Type Journal
ISBN 1096-9098 (Electronic) 0022-4790 (Linking)
Authors Thomas, D. M.; Ballinger, M. L.;
Responsible Garvan Author Prof David Thomas
Publisher Name JOURNAL OF SURGICAL ONCOLOGY
Published Date 2015-01-01 00:00:00
Published Volume 111
Published Issue 5
Published Pages 490-495
Status Published in-print
URL link to publisher's version http://www.ncbi.nlm.nih.gov/pubmed/25335907
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/12870