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Neuronal control of bone and muscle


The functional interplay between bone and muscle that enables locomotion is a fundamental aspect of daily life. However, other interactions between bone and muscle continue to attract attention as our understanding of the breath and importance of this inter-relationship continues to expand. Of particular interest is the regulatory connection between bone and muscle, which adds a new insight to the coordination of the bone/muscle unit. We have appreciated the importance of neuronal signaling to the control of bone turnover and muscle contraction, but recent data indicate that neuronal inputs control a far wider range of bone and muscle physiology than previously appreciated. This review outlines the role of the sympathetic nervous system and neuronal/neuropeptide inputs upon the regulation of bone and muscle tissue, and the potential for co-regulatory actions, particularly involving the sympathetic nervous system. This article is part of a Special Issue entitled

Type Journal
ISBN 1873-2763 (Electronic) 1873-2763 (Linking)
Authors Houweling, P. ; Kulkarni, R. N. ; Baldock, P. A.;
Responsible Garvan Author (missing name)
Publisher Name BONE
Published Date 2015-01-01
Published Volume 80
Published Pages 95-100
Status Published in-print
OpenAccess link to author's accepted manuscript version