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Adrenal tumours: how to establish malignancy


Adrenal masses are commonly found in the course of abdominal investigations and present diagnostic challenges. The foremost issue is whether the mass is the cause of the symptoms being investigated. Additional important clinical questions are: (1) is the adrenal mass benign or malignant and (2) whether the adrenal mass is functional or non-functional? We present a case of a 48-year-old man with severe abdominal pain. Imaging revealed a very large adrenal mass. Differential diagnostic procedures were performed and a diagnosis of primary adrenal lymphoma, an extremely rare cause of adrenal malignancy, was made. He proceeded to chemotherapy with cyclical cyclophosphamide, doxorubicin, etoposide and prednisolone, in addition to rituximab. This case illustrates the importance of establishing the nature of adrenal masses, to rapidly facilitate appropriate treatment.

Type Journal
ISBN 1757-790X (Electronic)
Authors Toogood, V. ; Milliken, S. ; Morey, A. ; Samaras, K.;
Publisher Name BMJ Case Rep
Published Date 2014-12-01
Published Volume 2014
Published Pages bcr2014203736-bcr2014203736
Status Published in-print
URL link to publisher's version
OpenAccess link to author's accepted manuscript version