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Human T Follicular Helper Cells in Primary Immunodeficiency: Quality Just as Important as Quantity

Abstract

T follicular helper (Tfh) cells are a subset of effector CD4(+) T cells specialised to induce Ab production by B cells. This review highlights some of the recent advances in the field of human Tfh cells that have come from the study of primary immunodeficiencies. In particular it is increasingly evident that the quality of the Tfh cells that are generated, is just as important as the quantity.

Type Journal
ISBN 1573-2592 (Electronic) 0271-9142 (Linking)
Authors Ma, C. S.;
Responsible Garvan Author Dr Cindy Ma
Publisher Name JOURNAL OF CLINICAL IMMUNOLOGY
Published Date 2016-01-01
Published Volume 36 Suppl 1
Published Pages 40-7
Status Published in-print
URL link to publisher's version http://www.ncbi.nlm.nih.gov/pubmed/26961358
OpenAccess link to author's accepted manuscript version https://publications.gimr.garvan.org.au/open-access/13737