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Genome-wide DNA methylation profiling in triple-negative breast cancer reveals epigenetic signatures with important clinical value

Abstract

Analysis of cancer methylomes has dramatically changed our concept of the potential of diagnostic and prognostic methylation biomarkers in disease stratification. Through whole-genome methylation capture sequencing of triple-negative breast cancers (TNBCs) we recently identified differentially methylated regions with diagnostic and prognostic value that promise to stratify TNBCs for more personalized management.

Type Journal
ISBN 2372-3556 (Linking)
Authors Stirzaker, C.; Zotenko, E.; Clark, S. J.;
Publisher Name MOLECULAR & CELLULAR ONCOLOGY
Published Date 2016-01-01 00:00:00
Published Volume 3
Published Issue 1
Published Pages e1038424
URL http://www.ncbi.nlm.nih.gov/pubmed/27308556
Status Published In-print
OpenAccess Link https://publications.gimr.garvan.org.au/download.php?13911_13690/2016-Stirzaker-Mol Cell Oncol.pdf