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Osteoporosis prevention and treatment

Abstract

Patients with low bone density or any prior low trauma fracture should be considered for therapeutic intervention. Oestrogen replacement therapy remains the first choice for prevention of bone loss in early postmenopausal women with low bone density. In postmenopausal women with existing fractures, the rank order of treatments is firstly alendronate, secondly raloxifene and thirdly less potent bisphosphonates, such as etidronate, or active vitamin D metabolites, such as calcitriol. For men with osteoporosis, if hypogonadism is present, it should be treated with testosterone replacement therapy. Despite limited data, a bisphosphonate should then be considered in conjunction with calcium. Supplementation with simple vitamin D should be considered in elderly patients who are housebound or live in institutions, as they are at risk of vitamin D deficiency and osteomalacia.

Type Journal
ISBN 0025-729X (Print)
Authors Sambrook, P. N.;Eisman, J. A. :
Publisher Name MEDICAL JOURNAL OF AUSTRALIA
Published Date 2000-01-01 00:00:00
Published Volume 172
Published Issue 5
Published Pages 226-9
URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10776395
Status Published In-print