The relationship between bronchial histamine reactivity and atopic status
It has been proposed that increased production of IgE, a feature of atopy, is a cause of the non-specific bronchial hyper-reactivity that is characterisitc of asthma. This hypothesis was examined by selecting groups of subjects with asthma or rhinitis and a group of healthy control subjects and studying the relationship between their bronchial histamine reactivity and their atopic status. In none of the groups tested was there a significant association between the degree of bronchial histamine reactivity and either the serum level of total IgE or the number of extracts of aeroallergens giving positive prick test reactions.
|Authors||Bryant, D. H.;Burns, M. W. :|
|Publisher Name||Clin Allergy|
|Published Date||1976-01-01 00:00:00|