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The relationship between bronchial histamine reactivity and atopic status


It has been proposed that increased production of IgE, a feature of atopy, is a cause of the non-specific bronchial hyper-reactivity that is characterisitc of asthma. This hypothesis was examined by selecting groups of subjects with asthma or rhinitis and a group of healthy control subjects and studying the relationship between their bronchial histamine reactivity and their atopic status. In none of the groups tested was there a significant association between the degree of bronchial histamine reactivity and either the serum level of total IgE or the number of extracts of aeroallergens giving positive prick test reactions.

Type Journal
ISBN 0009-9090 (Print)
Authors Bryant, D. H.;Burns, M. W. :
Publisher Name Clin Allergy
Published Date 1976-01-01
Published Volume 6
Published Issue 4
Published Pages 373-81
Status Published in-print
URL link to publisher's version