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Here, there and everywhere: T follicular helper cells on the move

Abstract

T follicular helper (Tfh) cells have the important function of providing B-cell help for the induction of antigen-specific antibody production. As such, it is important to determine the factors that regulate the development, differentiation and function of Tfh cells. This review highlights some of the recent advances in our understanding of Tfh cell migration, Tfh cell memory and the origins and fate of circulating Tfh cells in the blood, that have been revealed from studies in humans and mice.

Type Journal
ISBN 1365-2567 (Electronic) 0019-2805 (Linking)
Authors Ma, C. S.; Phan, T. G.
Responsible Garvan Author A/Prof Cindy Ma
Publisher Name IMMUNOLOGY
Published Date 2017-11-01
Published Volume 152
Published Issue 3
Published Pages 382-387
Status Published in-print
DOI 10.1111/imm.12793
URL link to publisher's version https://www.ncbi.nlm.nih.gov/pubmed/28704588