Publications

Publications Search

Search for publications by author
Search for publications by abstract keyword(s)

SnapShot: Phosphoregulation of Mitosis

Abstract

During mitosis, a cell divides its duplicated genome into two identical daughter cells. This process must occur without errors to prevent proliferative diseases (e.g., cancer). A key mechanism controlling mitosis is the precise timing of more than 32,000 phosphorylation and dephosphorylation events by a network of kinases and counterbalancing phosphatases. The identity, magnitude, and temporal regulation of these events have emerged recently, largely from advances in mass spectrometry. Here, we show phosphoevents currently believed to be key regulators of mitosis. For an animated version of this SnapShot, please see http://www.cell.com/cell/enhanced/odonoghue2.

Type Journal
ISBN 1097-4172 (Electronic) 0092-8674 (Linking)
Authors Burgess, A.; Vuong, J.; Rogers, S.; Malumbres, M.; O'Donoghue, S. I.
Responsible Garvan Author Dr Andrew Burgess
Publisher Name CELL
Published Date 2017-06-30
Published Volume 169
Published Issue 7
Published Pages 1358-1358.e1
Status Published in-print
DOI 10.1016/j.cell.2017.06.003
URL link to publisher's version https://www.ncbi.nlm.nih.gov/pubmed/28622516