Cancer and the omics revolution
BACKGROUND: Internal medicine is in flux because of the 'omics revolution', with cancer medicine being a good example. Molecular technologies that detect alterations in gene-based structure or function are having an impact on diagnosis, prognosis and treatment of cancer. OBJECTIVE: In this article, recent advances in gene-based characterisation of cancer are presented, and illustrated where possible by clinical applications. DISCUSSION: The research-based vision of precision medicine is now on its way to becoming a clinical reality. A key limiting factor is the small number of therapeutic options available for customisation, which contrasts with the rising abundance of omics-derived data. However, further translational progress is anticipated over the next decade.
|ISBN||0300-8495 (Print) 0300-8495 (Linking)|
|Authors||Epstein, R. J.; Lin, F. P.|
|Responsible Garvan Author|
|Publisher Name||Australian Family Physician|
|Published Date||2017-04-30 00:00:00|
|URL link to publisher's version||https://www.ncbi.nlm.nih.gov/pubmed/28376570|