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Cancer and the omics revolution

Abstract

BACKGROUND: Internal medicine is in flux because of the 'omics revolution', with cancer medicine being a good example. Molecular technologies that detect alterations in gene-based structure or function are having an impact on diagnosis, prognosis and treatment of cancer. OBJECTIVE: In this article, recent advances in gene-based characterisation of cancer are presented, and illustrated where possible by clinical applications. DISCUSSION: The research-based vision of precision medicine is now on its way to becoming a clinical reality. A key limiting factor is the small number of therapeutic options available for customisation, which contrasts with the rising abundance of omics-derived data. However, further translational progress is anticipated over the next decade.

Type Journal
ISBN 0300-8495 (Print) 0300-8495 (Linking)
Authors Epstein, R. J.; Lin, F. P.
Responsible Garvan Author Prof Richard Epstein
Publisher Name Australian Family Physician
Published Date 2017-04-30
Published Volume 46
Published Issue 4
Published Pages 189-193
Status Published in-print
URL link to publisher's version https://www.ncbi.nlm.nih.gov/pubmed/28376570