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Release of secretin--plasma levels reproduced by exogenous infusion


Infusion of 0.1 M HCl (0.5 mmol/kg/hr over 20 minutes) into the duodenum of each of seven normal subjects led to a significant rise (P less than 0.05) in mean plasma secretion levels from 3.0 +/- 2.2 (SE) to 15 +/- 4.0 pmol/l. Intravenous infusion of secretin at a rate of 6.6 pmol/kg/hr (0.08 clinical units/kg/hr) reproduced the peak plasma levels of secretin observed during duodenal acidification. However, there was no detectable (2.5 pmol/l) change in plasma secretin after oral protein or glucose.

Type Journal
ISBN 0004-8291 (Print)
Authors Byrnes, D. J.;Marjason, J.;Henderson, L.;Lazarus, L. :
Publisher Name Aust N Z J Med
Published Date 1979-01-01
Published Volume 9
Published Issue 2
Published Pages 151-3
Status Published in-print
URL link to publisher's version