Development of a closed-loop artificial pancreas
A closed-loop glucose controlled insulin infusion system was developed, consisting of elements for continuous blood glucose analysis, a computer control system, and infusion systems. Improvements include decreased size, cost reduction and better performance. The algorithm used was a piecewise linear representation of the sigmoidal curve commonly employed. The apparatus has been applied to simulation of the healthy beta cell and glucose clamp studies.
|Authors||Kraegen, E. W.;Whiteside, R.;Bell, D.;Chia, Y. O.;Lazarus, L. :|
|Publisher Name||Horm Metab Res Suppl|
|Published Date||1979-01-01 00:00:00|