Risk factors for vitamin D inadequacy among women with osteoporosis: an international epidemiological study
A serum 25-hydroxyvitamin D [25(OH)D] level of 75 nmol/l (30 ng/ml) has been proposed as the minimum for adequate vitamin D nutrition as lower levels are associated with increases in serum parathyroid hormone in otherwise healthy adults. Amongst 2589 community-dwelling, postmenopausal women with osteoporosis from 18 countries, recruited to determine risk factors for vitamin D inadequacy, 64% had vitamin D inadequacy. General health, education, ethnicity, sun exposure, skin reactivity, diet, recent travel to sunny climates, vitamin D supplementation, body mass index (BMI), season and latitude were assessed using logistic regression models. Asian ethnicity, BMI >or=30 kg/m(2), living in non-equatorial countries, inadequate vitamin D supplementation, poor/fair health, no education about vitamin D, skin reactivity and no recent travel to sunny areas were significant predictors. Several modifiable risk factors are associated with vitamin D inadequacy worldwide, suggesting potentially simple ways to increase vitamin D and improve bone health in postmenopausal women.
|Authors||Rizzoli, R.;Eisman, J. A.;Norquist, J.;Ljunggren, O.;Krishnarajah, G.;Lim, S. K.;Chandler, J. :|
|Responsible Garvan Author||Prof John Eisman|
|Publisher Name||INTERNATIONAL JOURNAL OF CLINICAL PRACTICE|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=16893446|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/2120|