T cell homeostasis
The pool of mature T cells comprises a heterogeneous mixture of naive and memory CD4(+) and CD8(+) cells. These cells are long lived at a population level but differ markedly in their relative rates of turnover and survival. Here, we review how contact with exogenous stimuli, notably self MHC ligands and various gamma(c) cytokines, plays a decisive role in controlling normal T cell homeostasis.Immunology and Cell Biology (2008) 86, 312-319; doi:10.1038/icb.2008.12; published online 25 March 2008.
|Authors||Sprent, J.;Cho, J. H.;Boyman, O.;Surh, C. D. :|
|Publisher Name||IMMUNOL CELL BIOL|
|Published Date||2008-01-01 00:00:00|
|OpenAccess Link||https://publications.gimr.garvan.org.au/download.php?2389_10022/08 Sprent IBC 86 312.pdf|