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Synovial complications of spondylepiphyseal dysplasia of late onset


We describe 2 patients with a late-onset type of spondylepiphyseal dysplasia who developed multiple synovial complications. The synovial manifestations in the first patient included recurrent episodes of acute arthritis due to calcium pyrophosphate dihydrate crystal deposition and, later, chronic synovitis with radiologically evident chondrocalcinosis. In the second patient, cholesterol crystals in synovial fluid, multiple osteochondromata, and a histologic appearance resembling pigmented villonodular synovitis on synovial biopsy were seen. Osteochondromata were identified in 4 other members of this patient's family. Synovial manifestations in the osteochondrodysplasias may be more common than previously recognized.

Type Journal
ISBN 0004-3591 (Print)
Authors Sambrook, P. N.;de Jager, J. P.;Champion, G. D.;Doust, B. D.;McGirr, E. E.;Kozlowski, K. S.;Sillence, D. O. :
Publisher Name ARTH RHEUM/AR C RES
Published Date 1988-01-01
Published Volume 31
Published Issue 2
Published Pages 282-7
Status Published in-print
URL link to publisher's version