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Resolution of apparent growth hormone-dependent growth failure during puberty: a case report


A prepubertal boy with apparent growth hormone (GH)-dependent growth failure displayed a marked increase in growth velocity, normal GH responses to arginine/insulin infusion and a fourfold increase in spontaneous 24-hour GH secretion following the onset of normal puberty. The case supports earlier observations of a transient form of GH insufficiency in some short prepubertal children, but represents the first evidence that puberty restores spontaneous as well as stimulated GH secretion in such patients.

Type Journal
ISBN 0301-0163 (Print)
Authors Weissberger, A. J.;Ho, K. Y.;Lazarus, L. :
Publisher Name Hormone Research in Paediatrics
Published Date 1989-01-01
Published Volume 32
Published Issue 4
Published Pages 148-50
Status Published in-print
URL link to publisher's version