Resolution of apparent growth hormone-dependent growth failure during puberty: a case report
A prepubertal boy with apparent growth hormone (GH)-dependent growth failure displayed a marked increase in growth velocity, normal GH responses to arginine/insulin infusion and a fourfold increase in spontaneous 24-hour GH secretion following the onset of normal puberty. The case supports earlier observations of a transient form of GH insufficiency in some short prepubertal children, but represents the first evidence that puberty restores spontaneous as well as stimulated GH secretion in such patients.
|Authors||Weissberger, A. J.;Ho, K. Y.;Lazarus, L. :|
|Publisher Name||Hormone Research in Paediatrics|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=2696721|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/594|