The role of receptor subtype diversity in the CNS
The molecular characterization of neuroreceptors and voltage-gated ion channels has revealed that receptor subtype heterogeneity is a common feature of chemical and electrical signal reception. The use of distinct genes encoding receptor subtypes is a favoured mechanism for generation of this diversity. We propose that the significance of the multiplicity and diversity of signal reception proteins is to increase the information-handling capacity of neurons. This may contribute to neural plasticity.
|Authors||Schofield, P. R.;Shivers, B. D.;Seeburg, P. H. :|
|Publisher Name||TRENDS IN NEUROSCIENCES|
|URL link to publisher's version||http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=1688675|
|OpenAccess link to author's accepted manuscript version||https://publications.gimr.garvan.org.au/open-access/637|