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Role of growth hormone in fluid homeostasis


Administration of human growth hormone (GH) is associated with clinically significant sodium retention. There is evidence that the antinatriuretic properties of GH are mediated by activation of the renin-angiotensin system, as well as a direct action on the kidney. The antinatriuretic properties of GH may be of pathophysiological significance in acromegaly, where increased body sodium and plasma volume occur, and may contribute to the development of hypertension in this condition.

Type Journal
ISBN 0301-0163 (Print)
Authors Ho, K. Y.;Kelly, J. J. :
Publisher Name Hormone Research in Paediatrics
Published Date 1991-01-01
Published Volume 36 Suppl 1
Published Pages 44-8
Status Published in-print
URL link to publisher's version
OpenAccess link to author's accepted manuscript version