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TLR2 activation promotes tumour growth and associates with patient survival and chemotherapy response in pancreatic ductal adenocarcinoma
Lundy, J.; Gearing, L. J.; Gao, H.; West, A. C.; McLeod, L.; Deswaerte, V.; Yu, L.; Porazinski, S.; Pajic, M.; Hertzog, P. J.; Croagh, D.; Jenkins, B. J.
ONCOGENE 2021 10.1038/s41388-021-01992-2
Development and validation of the risk engine for an Australian Health Economics Model of Osteoporosis
Si, L.; Eisman, J. A.; Winzenberg, T.; Sanders, K. M.; Center, J. R.; Nguyen, T. V.; Tran, T.; Palmer, A. J.
OSTEOPOROSIS INTERNATIONAL 2021 10.1007/s00198-021-05955-x
Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx((R)) Digital Spatial Profiler
Bergholtz, H.; Carter, J. M.; Cesano, A.; Cheang, M. C. U.; Church, S. E.; Divakar, P.; Fuhrman, C. A.; Goel, S.; Gong, J.; Guerriero, J. L.; Hoang, M. L.; Hwang, E. S.; Kuasne, H.; Lee, J.; Liang, Y.; Mittendorf, E. A.; Perez, J.; Prat, A.; Pusztai, L.; Reeves, J. W.; Riazalhosseini, Y.; Richer, J. K.; Sahin, O.; Sato, H.; Schlam, I.; Sorlie, T.; Stover, D. G.; Swain, S. M.; Swarbrick, A.; Thompson, E. A.; Tolaney, S. M.; Warren, S. E.; On Behalf Of The GeoMx Breast Cancer, Consortium
Cancers 13 (17) 2021 10.3390/cancers13174456
Cells of the human intestinal tract mapped across space and time
Elmentaite, R.; Kumasaka, N.; Roberts, K.; Fleming, A.; Dann, E.; King, H. W.; Kleshchevnikov, V.; Dabrowska, M.; Pritchard, S.; Bolt, L.; Vieira, S. F.; Mamanova, L.; Huang, N.; Perrone, F.; Goh Kai'En, I.; Lisgo, S. N.; Katan, M.; Leonard, S.; Oliver, T. R. W.; Hook, C. E.; Nayak, K.; Campos, L. S.; Dominguez Conde, C.; Stephenson, E.; Engelbert, J.; Botting, R. A.; Polanski, K.; van Dongen, S.; Patel, M.; Morgan, M. D.; Marioni, J. C.; Bayraktar, O. A.; Meyer, K. B.; He, X.; Barker, R. A.; Uhlig, H. H.; Mahbubani, K. T.; Saeb-Parsy, K.; Zilbauer, M.; Clatworthy, M. R.; Haniffa, M.; James, K. R.; Teichmann, S. A.
NATURE 597 (7875) :250-255, 2021 10.1038/s41586-021-03852-1
The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma
Valero, J. G.; Matas-Cespedes, A.; Arenas, F.; Rodriguez, V.; Carreras, J.; Serrat, N.; Guerrero-Hernandez, M.; Yahiaoui, A.; Balague, O.; Martin, S.; Capdevila, C.; Hernandez, L.; Magnano, L.; Rivas-Delgado, A.; Tannheimer, S.; Cid, M. C.; Campo, E.; Lopez-Guillermo, A.; Colomer, D.; Perez-Galan, P.
LEUKEMIA 35 (9) :2635-2649, 2021 10.1038/s41375-021-01201-9
Insulin resistance in type 1 diabetes managed with metformin (INTIMET): Study protocol of a double-blind placebo-controlled, randomised trial
Snaith, J. R.; Samocha-Bonet, D.; Evans, J.; Liu, Z.; Kowalski, G.; Bruce, C.; Holmes-Walker, D. J.; Greenfield, J. R.
DIABETIC MEDICINE 38 (9) :e14564, 2021 10.1111/dme.14564
Human transitional and IgM(low) mature naive B cells preserve permissive B-cell receptors
Zhang, Z., Jara, C. J., Singh, M., Xu, H., Goodnow, C. C., Jackson, K. J.,Reed, J. H.
IMMUNOLOGY AND CELL BIOLOGY 2021 10.1111/imcb.12478
Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs
Hewavisenti, R. V. Ferguson, A. L. Gasparini, G. Ohashi, T. Braun, A. Watkins, T. S. Miles, J. J. Elliott, M. Sierro, F. Feng, C. G. Britton, W. J. Gebhardt, T. Tangye, S. Palendira, U.
IMMUNOLOGY AND CELL BIOLOGY 2021 10.1111/imcb.12481
Aberrations in circulating ceramide levels are associated with poor clinical outcomes across localised and metastatic prostate cancer
Lin, H. M.; Huynh, K.; Kohli, M.; Tan, W.; Azad, A. A.; Yeung, N.; Mahon, K. L.; Mak, B.; Sutherland, P. D.; Shepherd, A.; Mellett, N.; Docanto, M.; Giles, C.; Centenera, M. M.; Butler, L. M.; Meikle, P. J.; Horvath, L. G.
PROSTATE CANCER AND PROSTATIC DISEASES 24 (3) :860-870, 2021 10.1038/s41391-021-00338-z
Ninjin'yoeito, a herbal medicine, enhances glucose tolerance in mice
Zhang, L.; Gopalasingam, G.; Herzog, H.
NEUROPEPTIDES 88 :102150, 2021 10.1016/j.npep.2021.102150
Regulation of neuropeptide Y in body microenvironments and its potential application in therapies: a review
Zhang, Y.; Liu, C. Y.; Chen, W. C.; Shi, Y. C.; Wang, C. M.; Lin, S.; He, H. F.
Cell and Bioscience 11 (1) :151, 2021 10.1186/s13578-021-00657-7
Neutrophil Interactions with the Lymphatic System
Jakovija, A.; Chtanova, T.
Cells 10 (8) 2021 10.3390/cells10082106
Significant detection of new germline pathogenic variants in Australian Pancreatic Cancer Screening Program participants
Murali, K.; Dwarte, T. M.; Nikfarjam, M.; Tucker, K. M.; Vaughan, R. B.; Efthymiou, M.; Collins, A.; Spigelman, A. D.; Salmon, L.; Johns, A. L.; Williams, D. B.; Delatycki, M. B.; John, T.; Stoita, A.
Hereditary Cancer in Clinical Practice 19 (1) :33, 2021 10.1186/s13053-021-00190-1
SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression
Russell, A. J.; Gray, P. E.; Ziegler, J. B.; Kim, Y. J.; Smith, S.; Sewell, W. A.; Goodnow, C. C.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 118 (34) 2021 10.1073/pnas.2110190118
Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease
Mulder, K.; Patel, A. A.; Kong, W. T.; Piot, C.; Halitzki, E.; Dunsmore, G.; Khalilnezhad, S.; Irac, S. E.; Dubuisson, A.; Chevrier, M.; Zhang, X. M.; Tam, J. K. C.; Lim, T. K. H.; Wong, R. M. M.; Pai, R.; Khalil, A. I. S.; Chow, P. K. H.; Wu, S. Z.; Al-Eryani, G.; Roden, D.; Swarbrick, A.; Chan, J. K. Y.; Albani, S.; Derosa, L.; Zitvogel, L.; Sharma, A.; Chen, J.; Silvin, A.; Bertoletti, A.; Bleriot, C.; Dutertre, C. A.; Ginhoux, F.
IMMUNITY 54 (8) :1883-1900 e5, 2021 10.1016/j.immuni.2021.07.007
Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition
Aziz, D.; Portman, N.; Fernandez, K. J.; Lee, C.; Alexandrou, S.; Llop-Guevara, A.; Phan, Z.; Yong, A.; Wilkinson, A.; Sergio, C. M.; Ferraro, D.; Etemadmoghadam, D.; Bowtell, D. D.; kConFab, Investigators; Serra, V.; Waring, P.; Lim, E.; Caldon, C. E.
NPJ Breast Cancer 7 (1) :111, 2021 10.1038/s41523-021-00312-x