A functioning immune system is critical to a healthy productive life. Vaccine-preventable infectious disease, allergy and autoimmunity pose a significant global health challenge. The COVID-19 pandemic has killed millions worldwide; allergies affect one in five Australians; and people with autoimmune diseases are burdened with chronic disability and ill health.
Our program seeks to make discoveries that will improve the diagnosis and treatment of autoimmune diseases, super-charge the immune response to vaccination, and transform the management of allergic diseases including anaphylaxis.
Our quest is powered by pioneering state-of-the-art technologies including single-cell analysis and clonal tracking, intravital imaging, gene editing and in vivo preclinical disease models.
We partner closely with colleagues including St Vincent’s Hospital, Sydney, St Vincent’s Centre for Applied Medical Research, along with UNSW Sydney School of Biomedical Sciences, UNSW School of Biotechnology and Biomolecular Sciences, the Kirby Institute, hospitals and Local Health Districts in Sydney and beyond.
Our aim is to develop new diagnostic approaches and more effective precision treatments that will change clinical practice and improve health outcomes in Australia and around the world.