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Increased tissue stiffness is a classic characteristic of solid tumors. One of the major contributing factors is increased density of collagen fibers in the extracellular matrix (ECM). Here, we investigate how cancer cel...
Purpose Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic subunit alpha ( PIK3CA) mutations are frequently observed in primary breast cancer. We evaluated their prognostic relevance by performing a pooled analysi...
Cyclin-dependent kinase (CDK4/6) inhibitors in combination with endocrine therapy are currently the optimal first line treatment for hormone receptor (HR) positive, human epidermal growth factor receptor 2 (HER2) non-amp...
Resistance to endocrine therapy is a significant therapeutic challenge in the treatment of women with hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) advanced breast cancer. Cyc...
OBJECTIVE: The purpose of this article is to describe the large number of radiotracers being evaluated for prostate-specific membrane antigen (PSMA) PET, which is becoming a central tool in the staging of prostate cancer...
To formulate clinical consensus recommendations on bone health assessment and management of women with oestrogen receptor-positive early breast cancer receiving endocrine therapy, representatives appointed by relevant Au...

The 2019 Garvan Researcher Awards

Jun 12, 2019 02:57 PM
Congratulations to the seven researchers who were presented with awards or prizes at the 2019 Garvan Researcher Awards event.

Terms and Conditions

Dec 07, 2018 01:31 PM

A genomic barcode tracker for immune cells

MEDIA RELEASE: Jul 17, 2019 08:22 AM
A new research method to pinpoint the immune cells that recognise cancer could significantly change how we treat the disease.

Making genomics teachable

Apr 01, 2019 04:30 PM
A Garvan-Weizmann collaboration is upskilling science teachers to educate students about genomics.
Nicotinamide adenine dinucleotide (NAD(+)) is modulated by conditions of metabolic stress and has been reported to decline with aging in preclinical models, but human data are sparse. Nicotinamide riboside (NR) supplemen...

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Nov 27, 2018 12:14 PM
Medical researcher, mountain runner, single-cell pioneer, father: Associate Professor Joseph Powell wears many hats. Now, he has joined Garvan as the Head of the Garvan-Weizmann Centre of Cellular Genomics, and as head o...

Our obesity research

Dec 18, 2017 02:30 PM

Obesity resources

Dec 18, 2017 02:30 PM