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About Sjögren’s syndrome
Dec 18, 2017 02:30 PM
In May 2016, the Division of Cancer Prevention and the Division of Cancer Control and Population Sciences, National Cancer Institute, convened a workshop to discuss a conceptual framework for identifying and genetically ...
Expression of galanin and the GALR1 galanin receptor subtype...
May 08, 2013 12:45 PM
Enhancement of Absolute Fracture Risk Prognosis with Genetic...
May 08, 2013 12:46 PM
An important objective of genetic research in osteoporosis is to translate genotype data into the prognosis of fracture. The present study sought to develop a prognostic model for predicting osteoporotic fracture by usin...
Ligand binding analysis of human neuropeptide Y1 receptor mu...
May 08, 2013 12:45 PM
Site-directed mutants of the human neuropeptide Y1 (NPY Y1) receptor expressed as a maltose binding protein fusion protein in E. coli show identical ligand binding parameters compared with the same mutants expressed in m...
Disrupted cardiac development but normal hematopoiesis in mi...
May 08, 2013 12:46 PM
Chemotactic cytokines (chemokines) attract immune cells, although their original evolutionary role may relate more closely with embryonic development. We noted differential expression of the chemokine receptor CXCR7 (RDC...
Time-dependent effects of Prkce deletion on glucose homeosta...
May 08, 2013 12:46 PM
AIMS/HYPOTHESIS: We examined the time-dependent effects of deletion of the gene encoding protein kinase C epsilon (Prkce) on glucose homeostasis, insulin secretion and hepatic lipid metabolism in fat-fed mice. METHODS: P...
Zoledronic acid prevents osteopenia and increases regenrate ...
May 08, 2013 12:45 PM
GSK3B polymorphisms alter transcription and splicing in Park...
May 08, 2013 12:45 PM
Parkinson's disease (PD) is a neurodegenerative disorder characterized by a combination of motor symptoms. We identified two functional single nucleotide polymorphisms in the glycogen synthase kinase-3beta gene (GSK3B). ...
We have previously shown that incubation for 1h with excess glucose or leucine causes insulin resistance in rat extensor digitorum longus (EDL) muscle by inhibiting AMP-activated protein kinase (AMPK). To examine the eve...
INTRODUCTION: Mammographic density (MD), after adjustment for a women's age and body mass index, is a strong and independent risk factor for breast cancer (BC). Although the BC risk attributable to increased MD is signif...
Clinical applications for vitamin D assays: what is known an...
May 08, 2013 12:46 PM
In this issue of Blood, Steward-Tharp et al report the generation of a murine model of the human primary immunodeficiency autosomal dominant hyperimmunoglobulin E (AD-HIES) syndrome and reveal novel insights and therapeu...
