Site Search

Search
The genetic determinants of osteoporosis remain poorly understood and there is a large unmet need for new treatments in our aging society. Thus, new approaches for gene discovery in skeletal disease are required to compl...
Bone mass and its mineral content are under genetic control. The vitamin D receptor (VDR) gene has been shown to be a major locus for genetic effects on bone mineral density (BMD), and polymorphisms in this gene accounte...

Pancreatic cancer

Feb 23, 2018 04:10 PM
Find information about pancreatic cancer, real life stories, and Garvan's research focus. We study the genetic characteristics of pancreatic cancer, prognosis and therapeutic responsiveness, and personalised medicine/tre...

Osteoporosis real lives

Dec 18, 2017 02:30 PM
KRAS mutated tumours represent a large fraction of human cancers, but the vast majority remains refractory to current clinical therapies. Thus, a deeper understanding of the molecular mechanisms triggered by KRAS oncogen...
Physical interaction between the cell surface receptors CD47 and signal regulatory protein alpha (SIRPalpha) was reported to regulate cell migration, phagocytosis, cytokine production, and macrophage fusion. However, it ...
Transduction of bone marrow stem cells with retroviral expression vectors represents a cheaper and more rapid alternative to conventional transgenesis for studies of in vivo gene function. Constitutive expression of retr...
B cells originate from precursors in the bone marrow, and the first cells which migrate to the peripheral blood have been classified as 'transitional B cells'. Transitional B cells have been characterized in human blood ...

Lupus

Jun 13, 2007 09:58 AM
Lupus, also known as systemic lupus erythematosus (SLE), is an autoimmune disease that causes various tissues in the body to become chronically inflamed.
Background and aims Glucocorticoids could impair vascular function directly, or indirectly by reducing insulin sensitivity. The aim of this study was to determine the direct and indirect effects of acute and chronic low...

Histopathology

Jan 13, 2014 03:17 PM

BUDGET 2018: A new national genomics mission for Australia

MEDIA RELEASE: May 09, 2018 09:53 AM
Garvan welcomes the announcement, in the newly released Federal Budget, of a new $500M genomics mission for Australia. The new mission seeks to save or transform the lives of more than 200,000 Australians through researc...
The role of increased lipid availability in the generation of insulin resistance by growth hormone has not been established. We investigated this in rats infused with saline (controls) or human growth hormone (hGH) (500 ...
Background: Breast cancers fall into two major classes depending on their estrogen receptor (ER) status. ER+ and ER- tumors have very different molecular phenotypes, and may have distinct cells of origin. ER- tumors ge...