Australia's worst health crisis is growing every year
It’s not just about a few extra kilos. Being overweight or obese puts people at serious risk of many other diseases. One of the most dangerous is type 2 diabetes and its precursor, prediabetes. These can cause high blood sugar levels, usually after meals. This can damage your organs and dramatically increases the risk of heart attack, stroke and kidney failure. But most people won’t know they have it — because there's often no clear symptoms.Watch the video
The answers could lie in our gut
Over time, we've seen how hard it is for patients who lose weight to keep the weight off. Even more puzzling, some individuals with prediabetes who did change their diet and lost weight, didn't improve their condition.
Dr Dorit Samocha-Bonet knew that if she wanted to solve these mysteries and help her patients, she had to go back to the research and find a fresh approach. When she heard about exciting research into the extraordinary effect of our gut microbiota on blood sugar levels after meals, she sensed she had a way forward.
She decided to take this research further and find out whether changing the gut microbiota with a personalised diet might increase the effectiveness of a common diabetes drug, metformin. Dr Samocha-Bonet believes it may unlock some of the mysteries around why some patients get better results than others.
The solution: groundbreaking research
Changing the gut microbiota with a personalised diet might increase the effectiveness of a common diabetes drug, metformin.
Our ultimate goal is to give clinicians and patients the diagnostic tools to deliver more personalised treatments – potentially preventing years of suffering for millions of people.
We know prediabetes can be reversed if it’s caught early and treated effectively.
That means that, with groundbreaking research like ours, we may be able to stop thousands, if not millions of Australians from progressing onto full-blown type 2 diabetes, which causes dramatic increases in the risk of heart attacks and strokes, kidney damage and blindness, among other complications.
How you can help
We’re making tremendous progress — but if we’re going to make serious inroads on diabetes, we can’t stop now. And like all bold medical research, it needs investment.
The future health of Australians depends on generous people. Your contribution could help millions of Australians.
Join the Personalised Medicine in Prediabetes (PREDICT) study
We are looking for people aged 20 - 70 years who have prediabetes or newly diagnosed type 2 diabetes but not treated with a glucose lowering medication.
The study involves taking a common diabetes medication and one of two diets; either a personalised diet (tailored to your gut microbes) or a standard healthy diet. All participants will use a food recording smartphone App during the study.
If you fit the above eligibility criteria and are interested in participating, please email the study team at firstname.lastname@example.org, or call us at 02 9295 8253. We can explain the study in more detail and check your eligibility then.
Due to COVID-19 and to protect the safety of participants and staff, the study will involve a maximum of 3 visits to the Garvan Institute in Darlinghurst, Sydney (next to St. Vincent’s Hospital) over a period of 7 months. Most of the follow up will be done over the phone or using video tools (e.g. Zoom or Skype). At the end of the study, you will be provided a $100 retail voucher