A/Prof Jodie Ingles

Laboratory Head

A/Prof Jodie Ingles

A/Prof Jodie Ingles is Head of the Clinical Genomics Laboratory at Centre for Population Genomics, The Garvan Institute of Medical Research and Murdoch Children’s Research Institute. She is a cardiac genetic counsellor in the Department of Cardiology, Royal Prince Alfred Hospital with more than 18 y

Biography

A/Prof Jodie Ingles is Head of the Clinical Genomics Laboratory at Centre for Population Genomics, The Garvan Institute of Medical Research and Murdoch Children’s Research Institute. She is a cardiac genetic counsellor in the Department of Cardiology, Royal Prince Alfred Hospital with more than 18 years' experience working with families with inherited heart diseases. She is an NHMRC Career Development Fellow, and received an NHMRC Excellence Award for the top ranked application in 2018. Her team is focused on finding ways to use cardiac genomics and genetic counselling to improve care, clarify diagnosis and refine risk information, and to implement these findings in to clinical care.

A/Prof Jodie Ingles is Head of the Clinical Genomics Laboratory at Centre for Population Genomics, The Garvan Institute of Medical Research and Murdoch Children’s Research Institute. She is a cardiac genetic counsellor in the Department of Cardiology, Royal Prince Alfred Hospital with more than 18 years' experience working with families with inherited heart diseases. She is an NHMRC Career Development Fellow, and received an NHMRC Excellence Award for the top ranked application in 2018. Her team is focused on finding ways to use cardiac genomics and genetic counselling to improve care, clarify diagnosis and refine risk information, and to implement these findings in to clinical care.

Awards and Honours

2019 - NHMRC Research Excellence Awards, Top-ranked CDF Level 1, Clinical category
2019 - Fellow of the Cardiac Society of Australia and New Zealand (FCSANZ)
2019 - Fellow of the Heart Rhythm Society (FHRS)
2017 - Cardiovascular Research Network (CVRN) Rising Star Ministerial Award
2012 - Rita and John Cornforth Medal for PhD achievement, University of Sydney
2012 - Peter Bancroft Prize for Research Work, Sydney Medical School, University of Sydney

Education

2014 - Master of Public Health (MPH)
University of Sydney, Australia

2011- Doctor of Philosophy (PhD)
University of Sydney, Australia

2002 - Graduate Diploma in Genetic Counselling
University of Newcastle, Australia

1999-2001- Bachelor of Biomedical Science
University of Newcastle, Australia

Selected Publications

Decision-making and experiences of preimplantation genetic diagnosis in inherited heart diseases.

European Journal of Human Genetics. 2021. Sept DOI: 10/1038/s41431-021-00963-1
Sex differences in hypertrophic cardiomyopathy: Interaction with genetics and environment. Current Heart

Failure Reports. 2021. Epub Sept DOI: 10.1007/s11897-021-00526-x
Sex disparities in sudden cardiac death. Circulation: Arrhythmia and Electrophysiology. 2021. Epub

Aug 17. DOI: 10.1161/CIRCEP.121.009834
An evidence-based assessment of genes in dilated cardiomyopathy. Circulation. 2021. July 6;

144(1):7-19. DOI: 10.116/CIRCULATIONAHA.120.053033
Global approaches to cardiogenetic evaluation after sudden cardiac death in the young: A survey among

healthcare professionals. Heart Rhythm. 2021. In press Mar 25. DOI: 10.1016/j.hrthm.2021.03.037 Clinical profile and health disparities in a multi-ethnic cohort of patients with hypertrophic cardiomyopathy.

Circulation: Heart Failure. 2021. 14(3):e007537 DOI: 10.1161/CIRCHEARTFAILURE.120.007537 Hypertrophic cardiomyopathy: Genetic testing and risk stratification. Current Cardiology Reports. 2021. Jan 12; 23(2):9 DOI: 10.1007/s11886-020-01437-4

 

Precision Medicine in Cardiovascular Disease: Part 1, Overview of Genetic Changes and Impact on Clinical Phenotypes and Disease. Journal of the American College of Cardiology. 2021. May 25. DOI: 10.1016/j.jacc.2020.12.071

What do we do and how do we do it? Assessing genetic counselling in the modern era (Editorial). European Journal of Human Genetics. 2020. Accepted Apr 9. DOI: 10.1038/s41431-020-0628-6

Genetic testing in inherited heart diseases. Heart Lung Circulation. 2020. 29(4):505-511. DOI: 10.1016/j.hlc.2019.10.014

Psychological issues in managing families with inherited cardiovascular diseases. Cold Spring Harbor Perspectives in Medicine. 2019. Accepted Aug 8. DOI: 10.1101/cshperspect.a036558

Evaluating the clinical validity of hypertrophic cardiomyopathy genes. Circ Genom Precis Med. 2019. Feb;12(2):e002460. DOI: 10.1161/CIRCGEN.119.002460

Evaluating a custom designed aid to improve communication of genetic results in families with hypertrophic cardiomyopathy: Study protocol for a randomised controlled trial. BMJ Open. 2019; 9(1):e026627. DOI: 10.1136/bmjopen-2018-026627

Psychological adaptation to molecular autopsy findings following sudden cardiac death in the young. Genetics in Medicine. 2018. Epub Oct 16. DOI: 10.1038/s41436-018-0338-4

Concealed arrhythmogenic right ventricular cardiomyopathy in sudden unexplained death events. Circulation: Genomic and Precision Medicine. 2018. Nov;11(11):e002355. DOI: 10.1161/CIRCGEN.118.002355

Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: Recommendations by ClinGen’s Inherited Cardiomyopathy Expert Panel. 2017. Genetics in Medicine. 20(3):351-359. DOI: 10.1038/gim.2017.218

Non-familial hypertrophic cardiomyopathy: Prevalence, natural history and clinical implications. Circulation: Cardiovascular Genetics. 2017. 10(2) pii: e001620. DOI: 10.1161/CIRCGENETICS.116.001620

A Prospective, Population-Based Study of Sudden Cardiac Death in the Young. New England Journal of Medicine 2016. 374(25):2441-52. DOI: 10.1056/NEJMoa1510687

Posttraumatic stress and prolonged grief after sudden cardiac death in the young. 2016. JAMA Internal Medicine. 176(3):402-5. DOI: 10.1001/jamainternmed.2015.7808