Dr Elysse Filipe

After graduating from the University of Lisbon (Portugal) with a MSc in Molecular biology and Genetics, I worked as a research assistant at the iMED institute in Lisbon where my work looked into establishing three-dimensional culture systems for mesenchymal stem cells and evaluating the potential fo
Research Officer

After graduating from the University of Lisbon (Portugal) with a MSc in Molecular biology and Genetics, I worked as a research assistant at the iMED institute in Lisbon where my work looked into establishing three-dimensional culture systems for mesenchymal stem cells and evaluating the potential for enhanced paracrine factor secretion, with applications in wound healing. Following that I moved to Sydney to begin my PhD at the Heart Research Institute where I joined the Applied Materials group under the supervision of Dr Steven Wise. My work looked into the potential of Bombyx mori (silkworm) silk as a biomaterial for artificial blood vessel engineering.

After completion of my PhD, I joined Dr Thomas Cox’s lab, where my research is now focused on understanding the interplay between the mechanical properties of tumours and their propensity to form metastasis.

Research Interests

Extracellular Matrix
Material Engineering
Cancer Metastasis

Education

2018, PhD, University of Sydney, Australia
2012, MSc, Molecular Biology and Genetics, University of Lisbon, Portugal
2009, BSc, Biomedical Sciences, University of the Algarve, Portugal

Selected Publications

Filipe, E,C., Santos, M., Hung J., Lee B.S.L., Ng, M.K.C., Rnjak-Kovacina, J., Wise, S.G. (2018) “Rapid endothelialization of off-the-shelf small diameter silk vascular grafts”. JACC: Basic to Translational Science.

Santos, M., Michael, P.L., Filipe, E.C., Tan, R. P., Chan, A.H.P,, Lee, B.S.L., Hung, J., Huynh, M., Hawkins, C., Waterhouse, A., Bilek, M.M.M, and Wise, S.G. (2018) “Nanocarriers synthesized from plasma dust capable of linker-free multifunctionalization”. ACS Nano Materials.

Kondyurina I, Wise S, Ngo A, Filipe E, Kondyurin A, Weiss A, Bao S, Bilek M.. (2017) “Plasma mediated protein immobilisation enhances the vascular compatibility of polyurethane with tissue matched mechanical properties”. Biomedical Materials. 12:045002

Santos, M., Filipe, E.C., Michael, P.L., Hung, J., Wise, S.G., Bilek, M.M.M.. (2016) “Mechanically Robust Plasma-Activated Interfaces Optimized for Vascular Stent Applications”. ACS Applied Materials and Interfaces. 8 (15), pp 9635–9650

Wise, S.G., Michael, P.L., Waterhouse, A., Santos, M., Filipe, E., Hung, J., Kondyurin, A., Bilek, MM., Ng, M.K.. (2015)“Immobilization of Bioactive Plasmin Reduces the Thrombogenicity of Metal Surfaces” Colloids and surfaces B: Biointerfaces. Dec 1;136:944-54

Yu, Y., Wise, SG., Michael, P.L., Bax, D.V., Yuen, G.S., Hiob, M.A., Yeo, G.C., Filipe, E.C., Dunn, L.L., Chan, K.H., Hajian, H., Celermajer, D.S., Weiss, A.S., Ng, M.K.. (2015) “Characterization of Endothelial Progenitor Cell Interactions with Human Tropoelastin”. PLoS ONE. 2015 Jun 26;10(6):e0131101.

Santos, J.M., Camões, S.P., Filipe, E., Cipriano, M., Barcia, R.N., Filipe, M., Teixeira, M., Simões, S., Gaspar, M., Mosqueira, D., Nascimento, D.S., Pinto-do-Ó, P., Cruz, P., Cruz, H., Castro M., Miranda, J.P.. (2015)“3D spheroid cell culture of umbilical cord tissue-derived MSCs (UCX(R)) leads to enhanced paracrine induction of wound healing”. Stem Cell Research and Therapy. May 9;6:90

Miranda, J.P*., Filipe, E*., Fernandes, A.S., Almeida, J.M., Martins, J.P., De la Fuente, A., Abal, M., Barcia, R.N., Cruz, P., Cruz, H., Castro, M., Santos, J.M.. (2015) “The Human Umbilical Cord Tissue-Derived MSC Population UCX® Promotes Early Motogenic Effects on Keratinocytes and Fibroblasts and G-CSF-Mediated Mobilization of BM-MSCs When Transplanted In Vivo”. Cell Transplantation. 24(5):865-77

Person portrait

Dr Elysse Filipe

Research group