Dr Venessa Chin

Dr Venessa Chin

Venessa is a Medical Oncologist working at The Kinghorn Cancer Centre in the fields of lung and head and neck cancer.  She worked with the Personalised Cancer Therapeutics group during her PhD, which looked at using genomics to inform therapeutic discoveries in pancreas cancer.  Her work included a

Biography

Venessa is a Medical Oncologist working at The Kinghorn Cancer Centre in the fields of lung and head and neck cancer.  She worked with the Personalised Cancer Therapeutics group during her PhD, which looked at using genomics to inform therapeutic discoveries in pancreas cancer.  Her work included a meta-analysis, in vitro and in vivo analysis of rationally selected drug targets, and analysis of metastasis formation in real time. 

She is now part of the Cancer Developmental Biology group, where she is the lung cancer research fellow.  Here she is working on the genomic events which drive primary and metastasis formation in non small cell and small cell lung cancer.

Venessa is a Medical Oncologist working at The Kinghorn Cancer Centre in the fields of lung and head and neck cancer.  She worked with the Personalised Cancer Therapeutics group during her PhD, which looked at using genomics to inform therapeutic discoveries in pancreas cancer.  Her work included a meta-analysis, in vitro and in vivo analysis of rationally selected drug targets, and analysis of metastasis formation in real time. 

She is now part of the Cancer Developmental Biology group, where she is the lung cancer research fellow.  Here she is working on the genomic events which drive primary and metastasis formation in non small cell and small cell lung cancer.

Awards and Honours

2014 - Best young oncologist oral presentation
2013 - NHMRC full PhD scholarship
2013 - Pancare full PhD scholarship
2013 - Sydney Catalyst full PhD scholarship
2011 - RACP - Research entry scholarship

Education

2017 - PhD, UNSW Sydney (submitted) - Australia
2013 - FRACP
2003 - MBBS, University of Adelaide - Australia

Selected Publications

Vennin C, Chin V et al.  (co-first authorsTransient tissue ‘priming’ via ROCK manipulation uncouples pancreatic cancer progression, chemo-resistance and the onset of the metastatic niche.  Publication accepted to Science and Translational Medicine.

Chin V, et al.  Rho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunities. Expert Rev Mol Med. 2015

Nagrial AM, Chin VT et alSecond-line treatment in inoperable pancreatic adenocarcinoma: A systematic review and synthesis of all clinical trials.  Crit Rev Oncol Hematol. 2015 Dec;96(3):483-97

Jeremy L Humphris, Ann-Marie Patch, Katia Nones, Peter J Bailey, Amber L Johns, Skye McKay, David K Chang, David K Miller, Marina Pajic, Karin S Kassahn, Michael CJ Quinn, Timothy JC Bruxner, Angelika N Christ, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Craig Nourse, Ehsan Nourbakhsh, Andrew Stone, Peter J Wilson, Matthew Anderson, J Lynn Fink, Oliver Holmes, Stephen Kazakoff, Conrad Leonard, Felicity Newell, Nick Waddell, Scott Wood, Ronald S Mead, Qinying Xu, Jianmin Wu, Mark Pinese, Mark J Cowley, Marc D Jones, Adnan M Nagrial, Venessa T Chin et al. Hypermutation in pancreas cancer.  Gastroenterology. 2017, 152:1

Peter Bailey, David K. Chang, Katia Nones, Amber L. Johns , Ann-Marie Patch, Marie-Claude Gingras, David K. Miller, Angelika N. Christ, Tim J. C. Bruxner, Michael C. Quinn, Craig Nourse, L. Charles Murtaugh, Ivon Harliwong, Senel Idrisoglu, Suzanne Manning, Ehsan Nourbakhsh1, Shivangi Wani, Lynn Fink, Oliver Holmes, Venessa Chin, et al.  Genomic analyses identify molecular subtypes of pancreatic cancer.  Nature. 2016 Mar 3;531(7592):47-52

N Waddell, M Pajic, A Patch, D Chang, K Kassahn, P Bailey, A Johns, D Miller, K Nones, K Quek, M Quinn, A Robertson, M Fadlullah, T Bruxner, A Christ, I Harliwong, S Idrisoglu, S Manning, C Nourse, E Nourbakhsh, S Wani, P Wilson, E Markham, N Cloonan, M Anderson, L Fink, Oliver Holmes , Stephen Kazakoff , Conrad Leonard , Felicity Newell , S Song, D Taylor, S Wood, Q Xu, J Wu, M Pinese, M Cowley, M Jones, E Colvin, A Nagrial, E Humphrey, L Chantrill, A Mawson, J Humphris, A Chou, C Scarlett, A Pinho, I Rooman, J Samra, J Kench, J Lovell, N Merrett, C Toon, K Epari, N Nguyen, A Barbour, N Zeps, N Jamieson, J Graham, R Gruetzmann, R Hruban, A Maitra, C Iacobuzio-Donahue, C Wolfgang, R Morgan, R Lawlor, V Corbo, C Bassi, M Falconi, G Zamboni, G Tortora, M Tempero, J Eshleman, C Pilarsky, A Scarpa, E Musgrove, M Giry-latterriere, A Gill, J Pearson, S Grimmond, D Aust , V Chin et al. Whole Genomes Redefine the Mutational Landscape of Pancreatic Cancer.  Nature. 2015 Feb 26;518 (7540)

Biankin AV, Waddell N, Kassahn KS, Gingras MC, Muthuswamy LB, Johns AL, Miller DK, Wilson PJ, Patch AM, Wu J, Chang DK, Cowley MJ, Gardiner BB, Song S, Harliwong I, Idrisoglu S, Nourse C, Nourbakhsh E, Manning S, Wani S, Gongora M, Pajic M, Scarlett CJ, Gill AJ, Pinho AV, Rooman I, Anderson M, Holmes O, Leonard C, Taylor D, Wood S, Xu Q, Nones K, Fink JL, Christ A, Bruxner T, Cloonan N, Kolle G, Newell F, Pinese M, Mead RS, Humphris JL, Kaplan W, Jones MD, Colvin EK, Nagrial AM, Humphrey ES, Chou A, Chin VT, et alPancreatic cancer genomes reveal aberrations in axon guidance pathway genes.  Nature. 2012 Nov 15;491(7424):399-405

Pajic M, Herrmann D, Vennin C, Conway J, Chin VT et al. The dynamics of Rho GTPase signalling and implications for targeting cancer and the tumour microenvironment.  Small GTPases. 2015 Jun 23:1-11

Sjoquist K, Chin VT et alPersonalising pancreas cancer treatment: when tissue is the issue.  World Journal of Gastroenterology 2014 Jun 28;20(24):7849-63