Chenxu Yan

Role: PhD Student
Lab/Group: Brink Lab

Selected publications

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2026
Molecular Metabolism10.1016/j.molmet.2026.102320
Protein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice.
Amanda E Brandon, Chenxu Yan, Xuan Zhang, Chi Kin Ip, Zhongmin Gao, Nicola J Lee, Oana C Marian, Alex Perez, Anthony S Don, Herbert Herzog, Lewin Small, Yan-Chuan Shi, Carsten Schmitz-Peiffer
2025
The Journal of Endocrinology10.1530/JOE-25-0233
Ambient Temperature Modulates the Effects of Peripheral Y1R Antagonism on Diet-induced Obesity and Glucose Intolerance.
Chenxu Yan, Divyesh Dukshesh Naidu, Zhongmin Gao, Gopana Gopalasingam, Qi Wu, Chi Kin Ip, Hanyu Gao, Renjing Liu, Herbert Herzog, Yan-Chuan Shi
2025
Endocrinology10.1210/endocr/bqaf118
Emerging Insights into Brown Adipose Tissue Crosstalk With Pancreatic β-Cells in Metabolic Regulation.
Chenxu Yan, George Burley, Hanyu Gao, Yan-Chuan Shi
2025
Cell Reports10.1016/j.celrep.2025.115691
ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion.
Nancy Sue, Le May Thai, Ebru Boslem, Kwan Yi Chu, Chenxu Yan, Leanne Mackin, William E Hughes, Angela Fontaine-Titley, Deborah Barkauskas, Louise Cottle, Helen E Thomas, Carsten Schmitz-Peiffer, Yan-Chuan Shi, Paul Timpson, David Herrmann, Martin Whitham, Trevor J Biden
2023
Molecular Metabolism10.1016/j.molmet.2023.101845
Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation.
Nancy Sue, Le May Thai, Atsushi Saito, Cierra K Boyer, Ashleigh M Fordham, Chenxu Yan, Aimee Davenport, Jiang Tao, Mohammed Bensellam, James Cantley, Yan-Chuan Shi, Samuel B Stephens, Kazunori Imaizumi, Trevor J Biden

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Chenxu Yan

Selected publications

Protein kinase C epsilon deletion in AgRP neurons modulates hypothalamic glucose sensing and improves glucose tolerance in mice.

Ambient Temperature Modulates the Effects of Peripheral Y1R Antagonism on Diet-induced Obesity and Glucose Intolerance.

Emerging Insights into Brown Adipose Tissue Crosstalk With Pancreatic β-Cells in Metabolic Regulation.

ER stress disrupts insulin release in murine models of type 2 diabetes by impairing retromer action and constitutive secretion.

Independent activation of CREB3L2 by glucose fills a regulatory gap in mouse β-cells by co-ordinating insulin biosynthesis with secretory granule formation.