
Dr Diyana Hassanel
Dr Diyana Hassanel is a Research Officer at the Garvan Institute of Medical Research, where she leads the mRNA cancer vaccine project in the Sharma Lab. Her PhD research focused on synthesising and identifying novel hydrophilic polymer-lipids to stabilise mRNA lipid nanoparticle (LNP) formulations. This work improved gene expression and reduced nanoparticle clearance in vivo, and was published in the International Journal of Pharmaceutics and Nanoscale Horizons.
With expertise in mRNA LNP technology, Dr Hassanel is dedicated to advancing the development and optimisation of mRNA vaccine delivery systems for cancer applications. Within her first year as a postdoctoral researcher, she was awarded the competitive Therapeutic Innovation Australia (TIA) Pipeline Accelerator Scheme, which provides up to $50,000 in funding to support the progression of her preclinical research.
Awards
- 2025TIA Pipeline Accelerator Voucher Program Recipient
Selected publications
See all publications- 2025Nanoscale Horizons10.1039/d5nh00230c
Influence of hydrophilic polymers on the accelerated blood clearance of mRNA lipid nanoparticles upon repeated administration.
- 2024International Journal of Pharmaceutics10.1016/j.ijpharm.2024.124695
Replacing poly(ethylene glycol) with RAFT lipopolymers in mRNA lipid nanoparticle systems for effective gene delivery