Dr Leila Eshraghi

Role: Senior Research Officer
Lab/Group: Connie Johnson Breast Cancer Research Lab

Education

2013
Doctor of Philosophy (Doctor of Philosophy (Ph.D)), Molecular Biology
Murdoch University, Australia

Selected publications

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PUBLISHED 11 May 2026 Nature Communications
Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling
Authors:
Kristine J Fernandez, Ghazal Sultani, Max Nobis, Brian Gloss, Leila Eshraghi, [ ... ], Alexander Swarbrick, David Gallego-Ortega, Elgene Lim, Paul Timpson, C Elizabeth Caldon
PUBLISHED 17 December 2025 Science Translational Medicine
Dual PI3K/mTOR inhibition is required to combat resistance to CDK4/6 inhibitor and endocrine therapy in -mutant breast cancer
Authors:
Carla L Alves, Leena Karimi, Mikkel G Terp, Mie K Jakobsen, Fiona H Zhou, [ ... ], Leila Eshraghi, Sana Tamboowala, Ole N Jensen, Elgene Lim, Henrik J Ditzel
PUBLISHED 19 August 2025 Journal of Experimental & Clinical Cancer Research : CR
JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer
Authors:
Sarah Alexandrou, Christine S Lee, Kristine J Fernandez, Celine E Wiharja, Leila Eshraghi, [ ... ], Theresa E Hickey, Ewan K A Millar, Carla L Alves, Henrik J Ditzel, C Elizabeth Caldon
PUBLISHED 10 April 2024 Cellular and Molecular Life Sciences : CMLS
PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
Authors:
Hanna Tuppurainen, Niina Laurila, Marjut Nätynki, Leila Eshraghi, Anna Tervasmäki, Louisa Erichsen, Claus Storgaard Sørensen, Katri Pylkäs, Robert Winqvist, Hellevi Peltoketo
PUBLISHED 13 April 2021 Leukemia
Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer
Authors:
Deepak Singhal, Christopher N Hahn, Simone Feurstein, Li Yan A Wee, Luke Moma, [ ... ], Leila Eshraghi, [ ... ], Nicola K Poplawski, Daniel Thomas, Hamish S Scott, Lucy A Godley, Devendra K Hiwase

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Dr Leila Eshraghi

Education

Selected publications

Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling

Dual PI3K/mTOR inhibition is required to combat resistance to CDK4/6 inhibitor and endocrine therapy in -mutant breast cancer

JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer

PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling

Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer