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Sarah Alexandrou

Sarah Alexandrou

Role
Research Officer
Lab/Group
Caldon Lab

Selected publications

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  • 2026
    Nature Communications10.1038/s41467-026-70683-x

    Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling.

    Kristine J Fernandez, Ghazal Sultani, Max Nobis, Brian Gloss, Leila Eshraghi, Amy E McCart Reed, Sarah Alexandrou, Christine Lee, Daniel L Roden, Emily I Jones, Maryam Hasha Simad, Ewan K A Millar, Nenad Bartonicek, Samantha R Oakes, Fatima Valdes-Mora, Yolanda Colino-Sanguino, Ellie T Y Mok, Hannah L Williams, Jamie R Kutasovic, Margaret C Cummings, Janett Stoehr, Victoria Lee, Kate Harvey, Sunny Wu, Sunil R Lakhani, Peter T Simpson, Thomas R Cox, Lisa M Ooms, Christina A Mitchell, Rob Salomon, Alexander Swarbrick, David Gallego-Ortega, Elgene Lim, Paul Timpson, C Elizabeth Caldon
  • 2026
    Molecular Cancer10.1186/s12943-025-02510-8

    BRRIAR lncRNA alters breast cancer risk by modulating interferon signaling in cis and in trans.

    Haran Sivakumaran, Sneha Nair, Mainá Bitar, Xue Lu, Lu Wang, Ji Liu, Deshapriya S Karunarathne, P Prakrithi, Sebastien Jacquelin, Isela Sarahi Rivera, Kristine M Hillman, Susanne Kaufmann, Rebekah Ziegman, Wei Shi, Sarah Alexandrou, C Elizabeth Caldon, Rakesh N Veedu, Quan H Nguyen, Jonathan Beesley, Michelle N Wykes, Juliet D French, Stacey L Edwards
  • 2025
    Journal of Experimental & Clinical Cancer Research : CR10.1186/s13046-025-03466-9

    JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer.

    Sarah Alexandrou, Christine S Lee, Kristine J Fernandez, Celine E Wiharja, Leila Eshraghi, John Reeves, Daniel A Reed, Neil Portman, Zoe Phan, Heloisa Zaccaron Milioli, Iva Nikolic, Antonia L Cadell, David R Croucher, Kaylene J Simpson, Elgene Lim, Theresa E Hickey, Ewan K A Millar, Carla L Alves, Henrik J Ditzel, C Elizabeth Caldon
  • 2024
    Nature Structural & Molecular Biology10.1038/s41594-023-01181-7

    The potential of epigenetic therapy to target the 3D epigenome in endocrine-resistant breast cancer.

    Joanna Achinger-Kawecka, Clare Stirzaker, Neil Portman, Elyssa Campbell, Kee-Ming Chia, Qian Du, Geraldine Laven-Law, Shalima S Nair, Aliza Yong, Ashleigh Wilkinson, Samuel Clifton, Heloisa Zaccaron Milioli, Sarah Alexandrou, C Elizabeth Caldon, Jenny Song, Amanda Khoury, Braydon Meyer, Wenhan Chen, Ruth Pidsley, Wenjia Qu, Julia M W Gee, Anthony Schmitt, Emily S Wong, Theresa E Hickey, Elgene Lim, Susan J Clark
  • 2022
    Molecular Therapy : The Journal of the American Society of Gene Therapy10.1016/j.ymthe.2022.01.004

    miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma.

    Holly Holliday, Jessica Yang, Eoin Dodson, Iva Nikolic, Alvin Kamili, Madeleine Wheatley, Niantao Deng, Sarah Alexandrou, Thomas P Davis, Maria Kavallaris, C Elizabeth Caldon, Joshua McCarroll, Katleen De Preter, Pieter Mestdagh, Glenn M Marshall, Kaylene J Simpson, Jamie Fletcher, Alexander Swarbrick
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