Dr Sharissa Latham
Dr Sharissa Latham completed her PhD with Dr Valery Combes and Professor Georges Grau at the University of Sydney in 2015, where she studied the role of the actin cytoskeleton in extracellular vesicle shedding and specialised in advanced imaging methodologies incorporating both light and electron microscopy. Following her PhD, Sharissa commenced postdoctoral studies with Professor Dietmar Manstein at Hannover Medical School, Germany, where she investigated the role of actomyosin complexes in intracellular trafficking, sarcomere assembly and rare diseases. During this time, Sharissa co-led a study that characterised a previously undescribed actin-based disease, named ACTB-Associated Syndromic Thrombocytopenia (Latham et al., 2018, Nature Communications). Sharissa returned to Australia in 2018 to join Dr David Croucher in the Network Biology Group at the Garvan Institute of Medical Research. Building on her experience in cytoskeletal biology and advanced imaging approaches, Sharissa’s research aims to develop novel therapeutic approaches that target actin-microtubule crosstalk for the treatment of triple negative breast cancers.
- 2011Australian Vascular Biology Society (AVBS) meeting - presentation award
- 2012Miltenyi Biotec – travel award
- 2013Sydney Medical School Postgraduate Research Scholarship
- 2013Young Investigator Fellowship – 28th European Cytoskeletal Forum in Fribourg - Switzerland
- 2019Australian and New Zealand Society for Cell and Developmental Biology (ANZSCDB) Early Career Award - Hunter Meeting
- 2023Science advances10.1126/sciadv.abp8314
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma.
- Biochemical Society transactions10.1042/BST20220808
Non-kinase targeting of oncogenic c-Jun N-terminal kinase (JNK) signaling: the future of clinically viable cancer treatments.
- 2020Cell reports10.1016/j.celrep.2020.108090
Myosin-18B Regulates Higher-Order Organization of the Cardiac Sarcomere through Thin Filament Cross-Linking and Thick Filament Dynamics.
- Advances in experimental medicine and biology10.1007/978-3-030-38062-5_19