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Apr 21, 2022 03:59 PM

Rare genetic mutation linked to risk of severe viral infecti...

Identifying a rare genetic mutation that weakens the immune system can better inform those who may be at higher risk of severe viral illness.

Oct 28, 2021 08:15 AM

Tracking down the ‘elusive’ gene variant behind a devastatin...

Garvan-led CIRCA program uncovers the cause of a young family’s rare illness.

MEDIA RELEASE: Feb 01, 2021 01:48 PM

Inherited immune condition reversed by random DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

Dec 03, 2020 12:08 PM

Clinical guidance for two rare immune conditions revealed

A global clinical analysis has revealed 95% of children with two rare inborn immune conditions were effectively treated for lymphoma, when therapy occurred early.

Mar 12, 2020 08:38 AM

Research excellence acknowledged for Professor Stuart Tangye...

Professor Stuart Tangye has been awarded the 2019 NHMRC Peter Doherty Investigator Grant Award.

Dec 19, 2019 11:09 AM

Research reveals new drug target for autoimmune disease

A newly identified immune pathway could be altered with existing medication to treat autoimmune disease.

MEDIA RELEASE: Sep 19, 2019 08:53 AM

Extinct human species gave modern humans an immunity boost

Garvan researchers have discovered a gene variant that sheds new light on how human immunity was fine-tuned through history.

Sep 02, 2019 03:09 PM

NHMRC Investigator Grants for Garvan researchers

The NHMRC Investigator Grant Scheme will provide $8.5 million in funding to researchers at the Garvan Institute of Medical Research over the next five years, in recognition of their outstanding track records in research....

Jun 24, 2019 12:12 PM

CIRCA solves rare disease mysteries by combining expertise

A team of researchers and medical professionals are looking to answers in DNA to improve the lives of patients with rare immune conditions.

Apr 09, 2019 08:16 AM

The journey of solving a rare immune condition

A series of research publications from A/Prof Elissa Deenick and Prof Stuart Tangye has unpicked an intricate network of the human immune system.

Apr 08, 2019 01:28 PM

Professor Stuart Tangye receives prestigious Presidential Aw...

Professor Stuart Tangye, Leader of Immunity and Inflammatory Diseases research at Garvan, has been awarded the Clinical Immunology Society’s 2019 Presidential Award.

Feb 27, 2019 04:00 AM

Stella's story

Thanks to the Garvan-led research program CIRCA, patients living with critical, rare immune conditions are receiving life-saving treatment.

Dec 22, 2018 07:00 AM

The molecule at the centre of tuberculosis immunity

The key to better tuberculosis prevention – and to improving the odds for millions of patients globally – could lie in simply boosting the body’s natural levels of a small molecule.

Sep 03, 2018 05:27 PM

Gene-hunters make sense of a new immune disease

In an international quest for answers, Australian, French and American researchers have pulled back the curtain on a rare and mysterious disease – and exposed a new gene that can wreak havoc on the body’s defences. The t...

MEDIA RELEASE: Aug 23, 2018 06:30 AM

New 'micro-organ' was hiding in plain sight

For the first time in decades, researchers have identified a new anatomical structure within the immune system – and they say it’s an important step towards understanding how to make better vaccines.

Jul 14, 2017 11:30 AM

Immunotherapy – changing the way we think about cancer treat...

Garvan scientists are looking beyond their specialty areas and taking an inter-disciplinary approach that is changing the way we think about the treatment of cancer.

MEDIA RELEASE: May 11, 2017 12:05 AM

Proteins on the loose in a debilitating childhood disease

Australian scientists have shown, for the first time, that a family of untethered proteins builds up in the cells of children with a rare and serious genetic condition, known as mevalonate kinase deficiency (MKD).

Aug 26, 2016 03:03 PM

Unravelling the complexity of human immune disease gene by g...

In a series of recent studies, researchers from Garvan’s Immunology Division have shed light on the underlying biology disease in individuals suffering primary immunodeficiencies. Their findings have implications for pat...

Aug 07, 2015 11:26 AM

A piece in the puzzle of primary immunodeficiency

Research by Associate Professor Stuart Tangye and Dr Elissa Deenick, of Sydney’s Garvan Institute of Medical Research, has shed light on why some children are unusually susceptible to infectious disease.

MEDIA RELEASE: Apr 11, 2012 02:05 PM

Potential gene therapy for patients with rare disease

Australian scientists have discovered that a biological phenomenon known as ‘somatic reversion’, when an abnormal gene spontaneously becomes normal again, explains why some patients with a rare genetic disorder live much...

MEDIA RELEASE: Jan 11, 2010 06:00 PM

How a single molecule gives our immune systems their memory

By studying the blood cells of people with an immunodeficiency disorder, scientists at Garvan have been able to identify the molecular mechanisms that lead to the production of antibodies in human B cells. This has wider...