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Rebekah and her son Edmund went through a diagnostic odyssey to find the cause of Edmund's symptoms

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A bout of strep throat was the start of a diagnostic odyssey. The discovery of a rare genetic variant led to an effective therapy.


Edmund’s rare genetic variant uncovered a life-changing treatment

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Paspaley recently released the 'Kimberley Bracelet' to support Garvan 's cancer research. 20% of the purchase price is donated to Garvan, with Paspaley customers choosing which area of cancer research to support.

Paspaley 's Kimberley Bracelet for cancer research

A Garvan scientist, in collaboration with colleagues from Switzerland, has demonstrated for the first time how an important class of immune cells, 'Follicular dendritic cells ', essential for the development of antibodies, comes into being. The significance of their finding is underlined by its publication in the very prestigious international journal Cell. 

Understanding how a key group of immune cells is born

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Vale Constance (Connie) Johnson OAM 1977 – 2017.

Vale Connie Johnson OAM

Pancreatic cancer cells activate the molecule AKT (blue) to multiply and spread along connective stroma (pink) in the cancer environment. Credit: Max Nobis (VIB-KU Leuven Center for Cancer Biology)


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Image showing pancreatic cancer cells activating the molecule AKT (blue) to multiply and spread along connective stroma (pink) in the cancer environment. Credit: Max Nobis (VIB-KU Leuven Center for Cancer Biology)

Pancreatic cancer drug response and resistance has been uncovered in unprecedented detail, thanks to a research tool developed at the Garvan Institute.

Researchers image live drug response and resistant ‘pockets’ in pancreatic cancer

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Researchers are recruiting anyone affected by sudden cardiac arrest to a study aimed at improving support for those at risk.


Study to identify early warning signs of sudden cardiac arrest

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Thomas Cox and Jessica Chitty at the Garvan Institute

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Early laboratory results in mice show the drug PXS-5505 increases survival when combined with chemotherapy in the treatment of pancreatic ductal adenocarcinomas.


Drug that targets scar-like tissue in tumours shows promise for aggressive pancreatic cancer

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Dr Thomas Cox and Professor Chris Ormandy have been awarded three-year Project Grants from Cancer Council NSW to explore innovative research projects in pancreatic and breast cancer respectively.

Cancer Council NSW grants for innovative cancer research

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Targeting the tumour environment may help improve treatments for breast cancers affecting pregnant women and young mothers.

Inflammation a key to targeting pregnancy-associated breast cancer

The Australian Parkinson’s Mission, an innovative program combining clinical trials with genomics research for people with Parkinson’s, has received $30 million in Federal Government funding, the most significant investment in Australian Parkinson’s research.

Australian Parkinson’s Mission $30M funding boost

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Identifying a rare genetic mutation that weakens the immune system can better inform those who may be at higher risk of severe viral illness.

Rare genetic mutation linked to risk of severe viral infection in Polynesian populations

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State-of-the-art genomics will drive research into how the immune system’s response to a common virus affects our risk of developing multiple sclerosis.

MRFF funds Garvan-led multiple sclerosis research

Researchers examine imaging in the ACRF INCITe Centre at the Garvan Institute of Medical Research

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The new ACRF INCITe Centre provides world-leading microscope technology for unprecedented views of cancer and immune cell interactions, a game-changer for cancer research

ACRF INCITe Centre for world-class cancer imaging launches at the Garvan Institute

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Garvan and CSIRO researchers have uncovered key differences underlying harmful and non-harmful fat.

Genomic ‘map’ reveals not all fat is equal

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A study in zebrafish indicates that some genes linked to cancers in humans have been strictly regulated throughout evolution.

Ancient epigenetic changes silence cancer-linked genes

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A new research method to pinpoint the immune cells that recognise cancer could significantly change how we treat the disease.

A genomic barcode tracker for immune cells

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The Federal Government has awarded Professor Katherine Samaras a prestigious project grant to carry out critical dementia research.

Clinical trial to test diabetes treatment for dementia

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Targeting the tissue around pancreatic cancer cells may be the key to stopping their spread and improving chemotherapy outcomes.

Key to targeting the spread of pancreatic cancer

Jacqueline Center and Dana Bluic at the Garvan Institute

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A large cohort study has revealed a common osteoporosis drug significantly decreases premature mortality risk, likely related to a reduction in bone loss.

Osteoporosis drugs linked to reduced risk of premature death

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Australian researchers reveal new insights into retina’s genetic code

The NHMRC Investigator Grant Scheme will provide $8.5 million in funding to researchers at the Garvan Institute of Medical Research over the next five years, in recognition of their outstanding track records in research.

NHMRC Investigator Grants awarded to Garvan researchers

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Research reveals a new therapeutic target for the treatment of osteosarcoma.

Psoriasis drug target offers potential for osteosarcoma

Chris Goodnow, Shane Grey & Nathan Zammit

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Garvan researchers have discovered a gene variant that sheds new light on how human immunity was fine-tuned through history.

Extinct human species gave modern humans an immunity boost

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A step-by-step roadmap reveals the complex biological process of how cells copy their DNA.

The big picture of a microscopic event

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A landmark study pinpoints the birthplace of modern humans in southern Africa and suggests how past climate shifts drove their first migration.

The homeland of modern humans

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Professor Susan Clark FAA, has been awarded the 2019 NSW Premier’s Prize for Excellence in Medical Biological Sciences.

NSW Premier’s Prize honours epigenetics expert

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Researchers from across the Institute have been awarded seven grants from the St Vincent’s Clinic Foundation.

St Vincent’s Clinic Foundation Grants for Garvan researchers

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A potential treatment for pancreatic cancer shows promise in mice, reducing cancer spread by more than 60%.

Combination treatment shows promise for pancreatic cancer

Over six years, researchers evaluated the cognitive effects of statins in elderly consumers, revealing no negative impact and potential protective effects in those at risk of dementia.

Research reveals no link between statins and memory loss

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Virtual reality experience developed by a Garvan-led team allows users to explore the life inside a cell.

Genomics education steps into virtual reality in ‘Cell Explorer’

Simon Oaten, Omid Faridani, Julie Godfrey & Jenny Grainger

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Garvan’s Dr Omid Faridani has received the 2019 Pathfinders Award for his work developing a device that may personalise pancreatic cancer treatment.

New path forward for pancreatic cancer treatment

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A team of researchers and medical professionals are looking to answers in DNA to improve the lives of patients with rare immune conditions.

CIRCA solves rare disease mysteries by combining expertise

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Researchers are set to take the closest look at breast cancer yet to identify better ways of targeting the disease.

Garvan researchers to create an ‘Atlas’ for breast cancer

Garvan Neuroscience PhD student Ira Deveson, a member of Prof John Mattick’s RNA Biology and Plasticity lab, won the 2014 St Vincent’s Precinct Three Minute Thesis Competition on 12 June.

2014 St Vincent's Precinct Three Minute Thesis Competition

Ten PhD Students from across the St Vincent's Precinct have taken part in the annual Three Minute Thesis competition.

2019 St Vincent’s Precinct Three Minute Thesis competition

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Congratulations to the seven researchers who were presented with awards or prizes at the 2019 Garvan Researcher Awards event.

The 2019 Garvan Researcher Awards

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Emeritus Professor Edward (Ted) Kraegen AO has been recognised in the 2019 Queen’s Birthday Honours.

Queen’s Birthday Honours for Garvan’s Prof Ted Kraegen

Abhinav Humar, Jon Sprent and Fadi Lakkis

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Professor Jonathan Sprent has accepted the 2018 Thomas E. Starzl Prize in Surgery & Immunology at an award ceremony at the University of Pittsburgh.

Professor Jonathan Sprent awarded prestigious Starzl Prize

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Dr Mana Liao has been invited to help find solutions to the big questions facing the future of biotechnology.

Garvan Innovation Manager selected as ‘Leader of Tomorrow’

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Garvan’s Dr Venessa Chin has received a two-year Lung Foundation fellowship to undertake research to change the management of lung cancer.

Dr Venessa Chin receives Lung Foundation fellowship

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Professor Stuart Tangye has been awarded the 2019 NHMRC Peter Doherty Investigator Grant Award.

Research excellence acknowledged for Professor Stuart Tangye

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Four Garvan scientists will pioneer world-leading research on breast, pancreatic and bone cancer, thanks to funding from Cancer Council NSW.

Cancer Council funding for Garvan research

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Garvan congratulates PhD student Sarah Alexandrou who was awarded the annual Breast Cancer Award from Estée Lauder Companies.

Estée Lauder Award for novel breast cancer research project

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For his scientific leadership and pioneering research in molecular genetics Garvan’s Professor John Shine AC, has been elected as Fellow of the Royal Society.

Professor John Shine AC elected as Fellow of the Royal Society

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Whole genome sequencing at Garvan guided targeted therapy for a child with a severe autoimmune condition.

Gene sequencing guides girl’s life-changing arthritis treatment

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Garvan researchers will receive a total of $4.8 million in Investigator Grant funding through the National Health and Medical Research Council (NHMRC), for projects beginning in 2021.

NHMRC Investigator Grants for Garvan researchers

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Garvan’s urgent COVID-19 research has been awarded $590,000 in Government funding.

Federal support for Garvan COVID-19 research

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Garvan researchers reveal the tactic that cancer cells use to adapt and evade treatment.

Revealed: how cancer develops resistance to treatment

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Garvan researchers have revealed a way to potentially improve the efficacy of a common cancer treatment in lung adenocarcinoma patients.

Precision approach for lung adenocarcinoma

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Dr Owen Siggs has been awarded a prestigious 8-year fellowship to carry out crucial inflammatory disease research at the Garvan Institute.

Inflammatory disease in focus for fellowship recipient Dr Owen Siggs

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By Professor Chris Goodnow FAA FRS and first published in The Australian, 31 July 2020.

Key to treating COVID-19 will be found in our DNA

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Michael had suffered from mysterious medical symptoms his entire life. He received a life-changing treatment following a genetic diagnosis through the Garvan-led CIRCA program.

Researchers target immune system to treat rare cancer

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Garvan researchers have used cellular genomics to uncover promising therapy targets for triple negative breast cancer.

Breast cancer ‘ecosystem’ reveals possible new targets for treatment

Students at Garvan for the Day of Immunology

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A group of high school students visited the Garvan Institute to hear about what a career in biomedical research has to offer.

Day of Immunology: Garvan inspires students for STEMM

Weng Hua Khoo, Tri Phan and Peter Croucher

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Researchers have identified what keeps some cancer cells dormant – a finding which could uncover new approaches to preventing the spread of cancer.

Researchers reveal key to targeting dormant cancer cells

A Garvan-led research team called CIRCA is giving new hope to patients like Oscar, who are living with critical, rare immune conditions.

Discovering the unknown

Launched at the end of January 2019, the Australian Parkinson’s Mission is a world-first program integrating clinical trials with biomarkers and genomics that aims to slow, stop and ultimately cure Parkinson’s disease, a devastating illness that affects approximately 100,000 Australians today.

One step closer

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A series of research publications from A/Prof Elissa Deenick and Prof Stuart Tangye has unpicked an intricate network of the human immune system.

The journey of solving a rare immune condition

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Professor Stuart Tangye, Leader of Immunity and Inflammatory Diseases research at Garvan, has been awarded the Clinical Immunology Society’s 2019 Presidential Award.

Professor Stuart Tangye receives prestigious Presidential Award

Oliver Skinner, Marcia Munoz and Mike Rogers

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Australian scientists have uncovered part of the process that leads to ‘inflammatory flares’ in patients with a rare immune disorder.

A driver of inflammation in a rare childhood condition

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Garvan researchers have developed a method for detecting the products of ‘fusion’ genes in cancer cells more accurately than current clinical methods.

A more accurate method to diagnose cancer subtypes

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By fine-tuning how algorithms carve up DNA data, Garvan researchers have made it possible to do genomic analysis on a smartphone.

On-the-spot genome analysis

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The ‘mistakes’ in cancer DNA may be linked to not only how – but when – DNA is copied when cells divide.

Cancer DNA’s bad timing

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Thanks to the Garvan-led research program CIRCA, patients living with critical, rare immune conditions are receiving life-saving treatment.

Stella's story

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A new research project will allow patients and researchers to ‘see’ the drivers of cancer in virtual reality.

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Edmund’s rare genetic variant uncovered a life-changing treatment