
Professor Alexander Swarbrick
Professor Alex Swarbrick leads a multidisciplinary cancer research laboratory focussed on identifying new biomarkers and therapeutic strategies in breast and prostate cancer and melanoma. He is an international leader in the application of single-cell and spatially-resolved 'omics' to cancer. He leads the international Breast Cancer Cellular Atlas Consortium and co-leads Garvan's Strategic Program in Cancer Ecosystems with Professor Paul Timpson.
Alex graduated with a BSc (Hons I) in Molecular and Cellular Biology from UNSW in 1995. After obtaining his PhD in 2003 he undertook postdoctoral training with Nobel laureate J. Michael Bishop at the University of California, San Francisco, supported by a CJ Martin Travelling Fellowship from the NHMRC.
In 2008 he established the Tumour Progression Laboratory at Garvan and in 2012 was appointed co-Head of the Breast Translational Oncology Program in the newly commissioned Kinghorn Cancer Centre. Alex is a Professor at UNSW and an NHMRC Senior Leadership Investigator.
Alex is the founding co-convenor of the the Australian Translational Breast and Prostate Cancer Symposium and is the immediate-past convenor of the Lorne Cancer Conference, Australia's pre-eminent multi-disciplinary cancer research conference. He chairs the Cancer Research Committee of the Cancer Council NSW and is deputy chair of UNSW's Cancer Theme.
Medical Minds Podcast
Awards
- 2023
National Health and Medical Research Council Senior Leadership Investigator
- 2020
Petre Chair of Breast Cancer Research
- 2019
National Health and Medical Research Council Senior Research Fellowship
- 2013
National Health and Medical Research Council Career Development Fellowship II
- 2012
National Breast Cancer Foundation Fellowship
- 2011
NSW Premier’s Award for Outstanding Research Fellow 2011
- 2009
CINSW Early Career Fellowship
- 2007
Sydney University Medal for Excellence in Medical Research
Education
- 1995
Bachelor of Science (Bachelor of Science (B.S)), Molecular Biology
University of New South Wales, Australia
- 2003
Doctor of Philosophy (Doctor of Philosophy (Ph.D))
University of New South Wales, Australia
Selected publications
See all publications- PUBLISHED 6 September 2021Nature Genetics
A single-cell and spatially resolved atlas of human breast cancers
- PUBLISHED 13 August 2020The EMBO Journal
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer
- PUBLISHED 16 July 2019Nature Communications
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes
- PUBLISHED 24 July 2018Nature Communications
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
- PUBLISHED 7 November 2022Nature Communications
DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response
