Professor Alexander Swarbrick
Professor Alex Swarbrick leads a multidisciplinary cancer research laboratory focussed on identifying new biomarkers and therapeutic strategies in breast and prostate cancer and melanoma. He is an international leader in the application of single-cell and spatially-resolved 'omics' to cancer. He leads the international Breast Cancer Cellular Atlas Consortium and co-leads Garvan's Strategic Program in Cancer Ecosystems with Professor Paul Timpson. Alex graduated with a BSc (Hons I) in Molecular and Cellular Biology from UNSW in 1995. After obtaining his PhD in 2003 he undertook postdoctoral training with Nobel laureate J. Michael Bishop at the University of California, San Francisco, supported by a CJ Martin Travelling Fellowship from the NHMRC. In 2008 he established the Tumour Progression Laboratory at Garvan and in 2012 was appointed co-Head of the Breast Translational Oncology Program in the newly commissioned Kinghorn Cancer Centre. Alex is a Professor at UNSW and an NHMRC Senior Leadership Investigator. Alex is the founding co-convenor of the the Australian Translational Breast and Prostate Cancer Symposium and is the immediate-past convenor of the Lorne Cancer Conference, Australia's pre-eminent multi-disciplinary cancer research conference. He chairs the Cancer Research Committee of the Cancer Council NSW and is deputy chair of UNSW's Cancer Theme.
- 2007Sydney University Medal for Excellence in Medical Research
- 2009CINSW Early Career Fellowship
- 2011NSW Premier’s Award for Outstanding Research Fellow 2011
- 2012National Breast Cancer Foundation Fellowship
- 2013National Health and Medical Research Council Career Development Fellowship II
- 2019National Health and Medical Research Council Senior Research Fellowship
- 2020Petre Chair of Breast Cancer Research
- 2023National Health and Medical Research Council Senior Leadership Investigator
- 1995Bachelor of Science (Bachelor of Science (B.S)), Molecular BiologyUniversity of New South Wales, Australia
- 2003Doctor of Philosophy (Doctor of Philosophy (Ph.D))University of New South Wales, Australia
- 2021Nature genetics10.1038/s41588-021-00911-1
A single-cell and spatially resolved atlas of human breast cancers.
- 2020The EMBO journal10.15252/embj.2019104063
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer.
- 2019Nature communications10.1038/s41467-019-11049-4
High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes.
- 2018Nature communications10.1038/s41467-018-05220-6
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer.
- 2022Nature communications10.1038/s41467-022-34041-x
DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and immunotherapy response.