Professor Antony Basten
Professor Tony Basten is a clinician/scientist with a career spanning over 40 years. During this time, he has made a substantial contribution to our understanding of how the immune system is regulated in health and disease.
In 2007, Tony took sabbatical leave to spend time as a visiting fellow with Sir Gregory Winter FRS at the University of Cambridge, UK. Now, back at Garvan with the B Cell Biology group, he is continuing his work on the regulation of the immune system with a focus on the mechanisms that normally prevent unwanted responses (autoimmune and allergic); the ultimate goal being to devise novel ways of treating patients with these conditions.
Tony is a Non-Executive Director of BioTech Capital Limited and Apollo Life Sciences, and a member of the Scientific Advisory Board of Human Genetic Signatures.
Awards
- 2003Centenary Medal awarded by the Prime Minister of Australia for service to Australian society and immunology
- 1996Rotary International Award for Vocational Excellence
- 1992Fellowship of the Australian Academy of Science (FAA)
- 1984Rubbo Orator - Australian Society for Microbiology
- 1982Commonwealth Centres of Excellence Grants in Australia
- 1981Fellowship of the Australian Academy of Technological Sciences and Engineering (FTSE)
- 1980Inaugural Wellcome Australia Medal for 'distinguished discovery and its demonstrated use'
- 1979NHMRC Program Grants
Selected publications
See all publications- 2022Proceedings of the National Academy of Sciences of the United States of America10.1073/pnas.2123212119
Genetic and structural basis of the human anti-α-galactosyl antibody response.
- 2017Immunity10.1016/j.immuni.2017.11.022
CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity.
- 2017The Journal of Experimental Medicine10.1084/jem.20161533
Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells.
- 2015Immunity10.1016/j.immuni.2015.04.010
FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production.
- 2012Immunity10.1016/j.immuni.2012.07.017
Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.