Dr Astrid Magenau
After graduation from the University of Konstanz in Germany with a MSc in Immunology, Dr Astrid Magenau moved to Sydney to embark on a PhD at the Centre for Vascular Research at UNSW. During her PhD she focused on unravelling the role of membrane order and lipid rafts during phagocytosis by macrophages, using advanced imaging techniques. Since the laboratory Astrid was working in was a leader in the field of advanced microscopy methods, she decided to follow up the PhD with a post-doctoral position. During this time she contributed to the development and establishment of fluorescence-based super-resolution microscopy and used this technique to investigate the role of lipid membrane anchors in protein targeting to ordered domains in the cell membrane. At Garvan, Astrid joined Professor Paul Timpson’s Invasion and Metastasis Lab to apply advanced imaging techniques to the study of cancer invasion and metastasis.
- 2023Science advances10.1126/sciadv.adf9063
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
Cell-derived Matrix Assays to Assess Extracellular Matrix Architecture and Track Cell Movement.
- 2021Science advances10.1126/sciadv.abh0363
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.
- 2021Cell reports10.1016/j.celrep.2021.108945
Single-cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype.
- 2018Nature communications10.1038/s41467-018-07497-z
ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling.