Dr Jacqueline Tearle
Jacqueline completed her Ph.D. at EMBL Australia node in Single Molecule Science, UNSW, under the supervision of A/Prof. Maté Biro, where she used live-cell microscopy and single-cell transcriptomics to investigate cancer cell escape and invasion. She joined Garvan in 2022 as a Postdoctoral Researcher in the Gut Immunogenomics group, led by Dr. Kylie James. Jac’s current research involves using genomic and transcriptiomic approaches to characterise cellular and microbial drivers of intestinal disease. Jac is particularly interested in understanding the impact of modern lifestyle factors on gut health, and is passionate about using this information to develop more relevant therapies, reduce preventable gut pathologies, and support the societal change needed to protect future generations.
Awards
- 2025ASI MIMS Travel Bursary
- 2025GESA Mostyn Family Grant
- 2025GESA Project Grant
- 2024ASI Postdoctoral Travel Award
- 2024Tour de Cure Early Career Research Grant
- 2023EMBL Corporate Partnership Programme Fellowship
- 2023EMBL Fee Waiver Grant
- 2017UNSW Tuition Fee Scholarship 2017-2021
- 2015University of Birmingham Masters Scholarship
- 2012University of Birmingham Chamberlain Award
Selected publications
See all publications- 2023Cancer Research Communications10.1158/2767-9764.CRC-22-0305
Targeted Single-cell Isolation of Spontaneously Escaping Live Melanoma Cells for Comparative Transcriptomics.
- 2023Mucosal Immunology10.1016/j.mucimm.2023.11.004
Role reversals: non-canonical roles for immune and non-immune cells in the gut.
- 2020Journal of Cell Science10.1242/jcs.238014
The Lifeact-EGFP mouse is a translationally controlled fluorescent reporter of T cell activation.