Dr Katherine Jackson
Dr Katherine Jackson completed her PhD at the University of New South Wales investigating the inference of antigen selection from immunoglobulin heavy chain sequence data. Her research focuses on the application of immune receptor repertoire sequencing methodologies to study both immune responses to vaccination and infection and to study the genetics of the immune gene loci, with an interest in the role of individual immunogenetic variability and its impact on the development of antibody repertoires and immune responses. Following her PhD, Katherine has undertaken post-doctoral training at the University of New South Wales and Stanford University. During these roles she adapted methods developed during her doctoral studies to the larger immune receptor datasets that result from next generation sequencing platforms, and applied these to the monitoring B cell responses in vaccination and infection. Katherine’s current research continues to focus on utilising immune receptor repertoire sequencing to understand the evolution of responses in contexts ranging from primary vaccination (e.g. Rabies vaccination) and infection (e.g. Ebola virus, acute EBV), to secondary vaccination (e.g. seasonal influenza vaccination) and circumstances of autoimmunity or immune dysregulation.
- 2003Faculty of Science Award for best performance in honours
- 2003The Beckman Coulter prize for best performance in Honours in Bachelor of Science
- 2004Australian Postgraduate Award
- 2004The Baldwin Shelston Waters Prize for best performance in Professional Issues in Biotech
- 2007ASI Travel Award
- 2013ICI 2013 Bursaries to Young Immunologists
- 2014Paper of the Month (BABS UNSW)
- 2016Best Scientific Poster Prize (Stanford Pathology Retreat)
- 2023Clinical immunology (Orlando, Fla.)10.1016/j.clim.2023.109709
Diversification and expansion of the EBV-reactive cytotoxic T lymphocyte repertoire following autologous haematopoietic stem cell transplant for multiple sclerosis.
- 2022Clinical immunology (Orlando, Fla.)10.1016/j.clim.2022.109209
Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19.
- 2022Frontiers in immunology10.3389/fimmu.2022.1032911
High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells.
- 2022Frontiers in immunology10.3389/fimmu.2022.798300
Haematopoietic Stem Cell Transplantation Results in Extensive Remodelling of the Clonal T Cell Repertoire in Multiple Sclerosis.
- 2020The Journal of experimental medicine10.1084/jem.20191336
Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.