Dr Marcia Munoz
Dr Marcia Munoz started her PhD and early postdoctoral career at the Garvan Institute of Medical Research and the Children’s Cancer Institute, Sydney, as a cancer biologist focusing on the study of cell-intrinsic tumour-promoting signalling pathways, specifically a ubiquitin ligase involved in the DNA damage response and the role of ABC transporters in neuroblastoma. This led to a deep interest in the inflammatory tumour microenvironment and a post-doctoral position in Professor Wolfgang Weninger’s Immune Imaging Lab at the Centenary Institute. There, she used intravital microscopy to unveil the role of granzyme B in T cell extravasation and examined the dynamics of tumour-cytotoxic T cell interactions. In 2015 Marcia moved to the Bone Biology theme at Garvan. The Rogers lab seeks to understand the role of the mevalonate pathway in human health and disease, particularly in the context of inflammation and innate immunity. The lab’s focus is on the molecular pharmacology of bisphosphonate drugs used to treat metabolic bone diseases, and the pathophysiology of the autoinflammatory disease Mevalonate Kinase Deficiency.