Associate Professor Owen Siggs
Associate Professor Owen Siggs is a mid-career clinician-scientist and Snow Fellow. He is a member of the Garvan Faculty and Centre for Population Genomics, head of the Genomic Medicine Lab, and co-lead of the Garvan Rare Disease Program.
Owen trained in science and clinical medicine in Adelaide, in immunology and genomics at the John Curtin School of Medical Research with Professor Chris Goodnow, as a John Monash Scholar at The Scripps Research Institute in California with Nobel Laureate Professor Bruce Beutler, and at the University of Oxford with the Nuffield Professor of Medicine Richard Cornall. He was then a Sir Henry Wellcome Postdoctoral Fellow at the Wellcome Sanger Institute and a Junior Research Fellow at the University of Cambridge, and a Visiting Fellow at the Broad Institute of MIT and Harvard.
His current research interests lie in the genomic architecture of immune and ophthalmic disease, and leverage large clinical and genomic datasets, and new genomic technologies. He is actively engaged in the translation of these findings into clinical practice, particularly in the area of genomic risk prediction, and is a co-founder and director of Seonix Bio.
- 2007John Monash Scholar
- 2007Skaggs Oxford Scholar
- 2013Junior Research Fellow - University of Cambridge
- 2013Sir Henry Wellcome Postdoctoral Fellow
- 2021Dr. David L. Epstein Award
- 2021Snow Fellow
High Polygenic Risk Is Associated with Earlier Initiation and Escalation of Treatment in Early Primary Open-Angle Glaucoma.
- 2021JAMA ophthalmology10.1001/jamaophthalmol.2021.2440
Association of Monogenic and Polygenic Risk With the Prevalence of Open-Angle Glaucoma.
- 2019Nature immunology10.1038/s41590-019-0492-0
Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.