Dr Tatyana Chtanova
Dr Tatyana Chtanova graduated from the University of New South Wales with first class Honours in Biochemistry and Molecular Genetics in 1999. She was awarded her PhD in 2005 from UNSW for her thesis work on the identification of specific gene expression signatures for multiple T cell subsets, performed at the Garvan Institute of Medical Research under the supervision of Professor Charles Mackay.
Following her PhD, Tatyana obtained the highly competitive Human Frontier Science Program fellowship to train at University of California, Berkeley in the laboratory of Professor Ellen Robey. There she gained expertise in in vivo two-photon microscopy and used it to characterise, for the first time, neutrophil dynamics in vivo, and to identify a novel mechanism of immune evasion by pathogens via CD8 T cells.
Tatyana relocated to Garvan in May 2009 to establish her research laboratory within the Division of Immunology. Tatyana’s main research interest is immune cell migration in normal immune responses as well as in cancer. Tatyana’s group utilises a range of innovative techniques to analyse cell migration including in vivo two-photon microscopy as well as photoconvertible transgenic mouse systems.
Awards
- 2011 - 2013Human Frontier Science Program Career Development Award
- 2011 - 2015NHMRC Career Development Fellowship
- 2009 - 2012Cancer Institute NSW Career Development Award
- 2008Best Short Talk Award at FASEB Biology of the Immune System Summer conference
- 2005 - 2008Human Frontier Science Program Long-Term Fellowship
- 2004Keystone Symposia Travel Scholarship
- 2001 - 2003Australian Co-operative Research Center for Asthma scholarship
- 2001 - 2004University Postgraduate Research Scholarship –UNSW - Sydney - Australia
- 2001Australian Asthma Foundation Scholarship
Selected publications
See all publications- 2023Frontiers in Immunology10.3389/fimmu.2023.1060258
Skin immunity in wound healing and cancer.
- 2023Diabetes10.2337/db21-0841
Intracutaneous Transplantation of Islets Within a Biodegradable Temporizing Matrix as an Alternative Site for Islet Transplantation.
- 2023Kidney International10.1016/j.kint.2023.02.030
The impact of the cytoplasmic ubiquitin ligase TNFAIP3 gene variation on transcription factor NF-κB activation in acute kidney injury.
- 2023Cancer Research10.1158/0008-5472.CAN-21-4025
Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy.
- 2022Nature10.1038/s41586-022-05054-9
The retroelement Lx9 puts a brake on the immune response to virus infection.