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David Thomas

Professor David Thomas

Director Australian Genomic Cancer Medicine Centre

Professor David Thomas is CEO of Omico: the Australian Genomic Cancer Medicine Centre and inaugural Director of the Centre for Molecular Oncology at UNSW. He undertook his medical training at the University of Melbourne (1982-1988), followed by post-graduate training as a Fellow of the Royal Australasian College of Physicians in Medical Oncology (awarded 1997). He undertook his doctoral studies at the University of Melbourne, and was awarded his PhD in 1997. David undertook post-doctoral research at Harvard Medical School (1998-2000), before moving back to Melbourne to set up his own laboratory, initially at St Vincent’s Hospital (2001-2003), then at Peter MacCallum Cancer Centre (2002-2014). He was the founding Chair and board member of the Australasian Sarcoma Study Group (2007-18). He was the Director of the adolescent and young adult (AYA) cancer program, onTrac@PeterMac (2005-2010). In 2018, he was the President of the Connective Tissue Oncology Society. He heads the Garvan Institute of Medical Research’s Genomic Cancer Medicine Laboratory. In 2018, he established Omico, the Australian Genomic Cancer Medicine Centre.

Awards

  • 1998Neil Hamilton Fairley National Health and Medical Research Council Fellowship
  • 2000John Taplin Fellow - Harvard Medical School
  • 2002Arnott Fellowship - Royal Australasian College of Physicians
  • 2003Puzey fellowship - University of Melbourne
  • 2003RD Wright NHMRC Career Development Award
  • 2006Edna and Murray Dunn Award
  • 2007Victorian Cancer Agency - Clinician Researcher Fellowship
  • 2008Sam Sciacca Visiting Fellow - Queensland Cancer Council
  • 2009NHMRC Ten of the Best. Fellowship elected as one of the 10 best NHMRC investments for 2009
  • 2011Victorian Cancer Agency - Clinician Researcher Fellowship
  • 2012NHMRC Senior Research Fellow Level B
  • 2016NHMRC Principal Research Fellow
  • 2018President - Connective Tissue Oncology Society
  • 2020Herman Suit Lecturer - Connective Tissue Oncology Society

Selected Publications

See all publications
  • 2023
    Science (New York, N.Y.)10.1126/science.abj4784

    Heritable defects in telomere and mitotic function selectively predispose to sarcomas.

    Mandy L Ballinger, Swetansu Pattnaik, Piyushkumar A Mundra, Milita Zaheed, Emma Rath, Peter Priestley, Jonathan Baber, Isabelle Ray-Coquard, Nicholas Isambert, Sylvain Causeret, Winette T A van der Graaf, Ajay Puri, Florence Duffaud, Axel Le Cesne, Beatrice Seddon, Coonoor Chandrasekar, Joshua D Schiffman, Andrew S Brohl, Paul A James, Jean-Emmanuel Kurtz, Nicolas Penel, Ola Myklebost, Leonardo A Meza-Zepeda, Hilda Pickett, Maya Kansara, Nicola Waddell, Olga Kondrashova, John V Pearson, Andrew P Barbour, Shuai Li, Tuong L Nguyen, Diane Fatkin, Robert M Graham, Eleni Giannoulatou, Melissa J Green, Warren Kaplan, Shyamsundar Ravishankar, Joseph Copty, Joseph E Powell, Edwin Cuppen, Kristel van Eijk, Jan Veldink, Jin-Hee Ahn, Jeong Eun Kim, R Lor Randall, Kathy Tucker, Ian Judson, Rajiv Sarin, Thomas Ludwig, Emmanuelle Genin, Jean-Francois Deleuze, , Michelle Haber, Glenn Marshall, Murray J Cairns, Jean-Yves Blay, , David M Thomas, Martin Tattersall, Susan Neuhaus, Craig Lewis, Kathy Tucker, Richard Carey-Smith, David Wood, Sandro Porceddu, Ian Dickinson, Heather Thorne, Paul James, Isabelle Ray-Coquard, Jean-Yves Blay, Philippe Cassier, Axel Le Cesne, Florence Duffaud, Nicolas Penel, Nicolas Isambert, Jean-Emmanuel Kurtz, Ajay Puri, Rajiv Sarin, Jin-Hee Ahn, Jeong Eun Kim, Iain Ward, Ian Judson, Winette van der Graaf, Beatrice Seddon, Coonoor Chandrasekar, Rory Rickar, Ivo Hennig, Joshua Schiffman, R Lor Randall, Audrey Silvestri, Anaiis Zaratzian, Michael Tayao, Kelly Walwyn, Eveline Niedermayr, Denia Mang, Richard Clark, Tina Thorpe, Jessica MacDonald, Kim Riddell, Jasmine Mar, Vicki Fennelly, Allison Wicht, Belinda Zielony, Emma Galligan, Genna Glavich, Johanna Stoeckert, Lynda Williams, Lana Djandjgava, Iwona Buettner, Carla Osinki, Sonya Stephens, Muriel Rogasik, Laure Bouclier, Magali Girodet, Amandine Charreton, Yohan Fayet, Saniya Crasto, Bhanupriya Sandupatla, Yeon Yoon, Noda Je, Liz Thompson, Trent Fowler, Bella Johnson, Galina Petrikova, Thomas Hambridge, Angela Hutchins, Diego Bottero, Deborah Scanlon, Jo Stokes-Denson, Emmanuelle Génin, Dominique Campion, Jean-François Dartigues, Jean-François Deleuze, Jean-Charles Lambert, Richard Redon, Thomas Ludwig, Benjamin Grenier-Boley, Sébastien Letort, Pierre Lindenbaum, Vincent Meyer, Olivier Quenez, Christian Dina, Céline Bellenguez, Camille Charbonnier Le Clézio, Joanna Giemza, Stéphanie Chatel, Claude Férec, Hervé Le Marec, Luc Letenneur, Gaël Nicolas, Karen Rouault
  • 2022
    Nature medicine10.1038/s41591-022-01717-2

    Delivering precision oncology to patients with cancer.

    Joaquin Mateo, Lotte Steuten, Philippe Aftimos, Fabrice André, Mark Davies, Elena Garralda, Jan Geissler, Don Husereau, Iciar Martinez-Lopez, Nicola Normanno, Jorge S Reis-Filho, Stephen Stefani, David M Thomas, C Benedikt Westphalen, Emile Voest
  • 2021
    NPJ precision oncology10.1038/s41698-021-00194-z

    Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology.

    Frank P Lin, Subotheni Thavaneswaran, John P Grady, Mandy Ballinger, Maya Kansara, Samantha R Oakes, Jayesh Desai, Chee Khoon Lee, John Simes, David M Thomas
  • 2020
    Nature communications10.1038/s41467-019-14079-0

    The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.

    Mark Pinese, Paul Lacaze, Emma M Rath, Andrew Stone, Marie-Jo Brion, Adam Ameur, Sini Nagpal, Clare Puttick, Shane Husson, Dmitry Degrave, Tina Navin Cristina, Vivian F S Kahl, Aaron L Statham, Robyn L Woods, John J McNeil, Moeen Riaz, Margo Barr, Mark R Nelson, Christopher M Reid, Anne M Murray, Raj C Shah, Rory Wolfe, Joshua R Atkins, Chantel Fitzsimmons, Heath M Cairns, Melissa J Green, Vaughan J Carr, Mark J Cowley, Hilda A Pickett, Paul A James, Joseph E Powell, Warren Kaplan, Greg Gibson, Ulf Gyllensten, Murray J Cairns, Martin McNamara, Marcel E Dinger, David M Thomas
  • 2020
    Science (New York, N.Y.)10.1126/science.aau8768

    MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer.

    Arcadi Cipponi, David L Goode, Justin Bedo, Mark J McCabe, Marina Pajic, David R Croucher, Alvaro Gonzalez Rajal, Simon R Junankar, Darren N Saunders, Pavel Lobachevsky, Anthony T Papenfuss, Danielle Nessem, Max Nobis, Sean C Warren, Paul Timpson, Mark Cowley, Ana C Vargas, Min R Qiu, Daniele G Generali, Shivakumar Keerthikumar, Uyen Nguyen, Niall M Corcoran, Georgina V Long, Jean-Yves Blay, David M Thomas